Synthesis of Cinnamic Acid Derivatives
Lei Zhao, Yuanbiao Tu, Yuping Guo
Available Online February 2017.
- https://doi.org/10.2991/emcm-16.2017.85How to use a DOI?
- Cinnamic derivatives, Synthesis, Optimization
- Quinazoline derivatives have been shown to be biologically active such as afatinib. The cinnamic acid derivative is an important part of the quinazoline derivative which exerts its activity. And Cinnamic acid derivatives were prepared by the benzaldehyde derivatives and malonic acids. In this paper, four cinnamic acid derivatives were prepared. The structure was confirmed by MS and 1H NMR. In addition, this method not only saved the reaction time, but also improved the purity of the product. The yield of the step was about 90%.
- Open Access
- This is an open access article distributed under the CC BY-NC license.
Cite this article
TY - CONF AU - Lei Zhao AU - Yuanbiao Tu AU - Yuping Guo PY - 2017/02 DA - 2017/02 TI - Synthesis of Cinnamic Acid Derivatives BT - 2016 7th International Conference on Education, Management, Computer and Medicine (EMCM 2016) PB - Atlantis Press SN - 2352-538X UR - https://doi.org/10.2991/emcm-16.2017.85 DO - https://doi.org/10.2991/emcm-16.2017.85 ID - Zhao2017/02 ER -