Prevention of Antibiotic Resistance Micro Flora Spreading by Analysing Surgical Infections' Microbiological Profile
- 10.2991/hsic-17.2017.37How to use a DOI?
- Microbiological Profile; Clinical Isolates; Antibiotics Resistance; Antibiotics; Clinical Recommendations
Antibiotic resistance can be found among the top five most problematic issues that the international medical community pays a special attention to. The strategy of combating antibiotic resistance includes the rationalization of the antibiotic therapy, based on the regional specificity of the microbiological spectrum of diseases. Objectives: To investigate the microbiological profile of main groups of soft tissue surgical infections and acute surgical abdominal diseases in the Department of Surgery and develop further regional recommendations for the antimicrobial therapy. The methodology: Retrospective analysis (2012-2013 years) of operated patientsâ€™ bacteriological cultures in the Surgical Department of Lviv Communal City Clinical Emergency Hospital (Ukraine). The microflora of 646 samples (primary and secondary) was analyzed. 416 primary samples (2015 year) were studied separately to identify the resistance of the main pathogens. The analysis was carried out with the usage of the WHONET 5 database (standardized microbiological laboratory software). Results: In total, 12 microorganisms were detected: Gram-negative (58,3%) and Gram-positive (41,7%) bacteria. All results were sorted into the main surgical nosological groups: superficial infections of the skin and subcutaneous tissue (66%), necrotic infections of soft tissues and deep phlegmons (8,5%), acute surgical abdominal diseases (25,5%). S.aureus was the dominant pathogen in superficial infections of the skin and subcutaneous tissue (243 samples; 63,9%) and in necrotic infections and deep phlegmons (26 samples; 53,1%), and E.coli was in acute surgical abdominal diseases (49 samples; 33,3%). Particular attention was paid to antibiotic resistance of the clinical isolates of the dominant pathogen: generally, 37,3% strains of S.aureus were methicillin-resistant (MRSA), including multidrug-resistant strains. Conclusion: The data of the microbiological profile is the objective basis for the regional clinical antibiotic therapy recommendations in the Department of Surgery. Antimicrobial resistance research and surveillance may be effective to prevent the spread of antibiotic resistance microflora.
- © 2017, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Yuriy Lysiuk AU - Olena Pilipovich AU - Nataliia Pilipovich AU - Natalya Zakharko PY - 2017/10 DA - 2017/10 TI - Prevention of Antibiotic Resistance Micro Flora Spreading by Analysing Surgical Infections' Microbiological Profile BT - Proceedings of the Health Science International Conference (HSIC 2017) PB - Atlantis Press SP - 232 EP - 239 SN - 2468-5739 UR - https://doi.org/10.2991/hsic-17.2017.37 DO - 10.2991/hsic-17.2017.37 ID - Lysiuk2017/10 ER -