Identifying Medication-Related Problem in Secondary Stroke Prevention Therapy: A Cross-Sectional Study in Central Java, Indonesia

DOI

10.2991/978-94-6463-050-3_13How to use a DOI?

Keywords

secondary stroke prevention; ischemic; stroke; antiplatelet; antihypertensive; a lipid-lowering agent

Abstract

Stroke is the second leading cause of death globally after ischemic heart disease. Patients who survive the first stroke have a possibility to get a recurrent stroke. American Heart Association and the Indonesian Neurologist Association recommend secondary stroke prevention to minimize recurrent stroke. This study aims to evaluate the use of secondary stroke prevention, which includes antiplatelet, antihypertensive, and lipid-lowering agents on discharged patients after stroke events. This study applied the purposive sampling method by comparing patient medications with the guidelines. Data of medications from medical records were evaluated for an appropriate indication, contraindication, appropriate drug of choice, including combination, and appropriate dosage regimens. The number of samples in this study was 74 patients. The inclusion criteria were discharged patients who survived the first stroke. Patients diagnosed with hemorrhagic or transient ischemic attack and pregnant patients were excluded. Of 74 patients, 69 patients received antiplatelet, 73 patients received antihypertensive, and 18 patients received lipid-lowering agents. Based on the guideline, 74, 73, and 21 patients should get antiplatelet, antihypertensive, and lipid-lowering agents, respectively. Antiplatelet agents prescribed to 69 (93.24%) patients were appropriate. Antihypertensive therapy was prescribed to 73 patients: 59 (80.82%) patients were appropriate, while 19.18% were not appropriate. A lipid-lowering agent therapy prescribed to 18 (85.71%) patients was appropriate. Secondary stroke prevention medications were not prescribed to all stroke survivors. Untreated indications and inappropriate combinations of drugs are medication-related problems identified in secondary stroke prevention therapy.

Copyright

© 2023 The Author(s)

Open Access

Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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TY  - CONF
AU  - Hidayah Karuniawati
AU  - Zakky Cholisoh
AU  - Tanti Azizah Sujono
AU  - Laila Nisaul Hekmah
PY  - 2022
DA  - 2022/12/14
TI  - Identifying Medication-Related Problem in Secondary Stroke Prevention Therapy: A Cross-Sectional Study in Central Java, Indonesia
BT  - Proceedings of the 4th International Conference Current Breakthrough in Pharmacy (ICB-Pharma 2022)
PB  - Atlantis Press
SP  - 155
EP  - 163
SN  - 2590-3195
UR  - https://doi.org/10.2991/978-94-6463-050-3_13
DO  - 10.2991/978-94-6463-050-3_13
ID  - Karuniawati2022
ER  -