Proceedings of the 1st International Integrative Conference on Health, Life and Social Sciences (ICHLaS 2017)

Identification of Delta-Aminolevulinic Acid Dehydratase (ALAD) Gene Polymorphism in Students of Elementary School in Kalideres, Jakarta

Authors
Annisa Firdausi, Rini Puspitaningrum, Chris Adhiyanto, Nurmasari Sartono, Afifah izzati Afifah izzati
Corresponding Author
Annisa Firdausi
Available Online December 2017.
DOI
https://doi.org/10.2991/ichlas-17.2017.17How to use a DOI?
Keywords
Lead; Buccal mucosa cells; PCR-ARMS; Wildtype; Heterozigote
Abstract
Polymorphism in ALAD genes is form of adaptation mechanism environment changes due to pollutants Pb (Lead) and have an impact on the health risks. Accumulation of Pb in the lowest air pollutants may be a risk to children's health. Children with height range between 100 – 140 cm (6 to 9 years old) may have risks being exposed to Pb. Particulates Pb are found in ±1 meter above ground. The study was done to determine frequencies of genetic polymorphisms ALAD in population students of elementary school in Kalideres, Jakarta. The method used in this study was a descriptive method with laboratory test techniques using PCR-ARMS (Amplification Refractory Mutation System) technique and the completion of questionnaires by the parents for respondent characteristics. The samples were 60 students who were 51.7% were ALAD wildtypes, 48.3% heterozygotic genotypes, and no mutants were found in the population of elementary school children in Kalideres, Jakarta. This study is necessary to identify the individual's genetic susceptibility mainly in polymorphism ALAD gene.
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Proceedings
1st International Integrative Conference on Health, Life and Social Sciences (ICHLaS 2017)
Part of series
Advances in Health Sciences Research
Publication Date
December 2017
ISBN
978-94-6252-422-4
ISSN
2468-5739
DOI
https://doi.org/10.2991/ichlas-17.2017.17How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - CONF
AU  - Annisa Firdausi
AU  - Rini Puspitaningrum
AU  - Chris Adhiyanto
AU  - Nurmasari Sartono
AU  - Afifah izzati Afifah izzati
PY  - 2017/12
DA  - 2017/12
TI  - Identification of Delta-Aminolevulinic Acid Dehydratase (ALAD) Gene Polymorphism in Students of Elementary School in Kalideres, Jakarta
BT  - 1st International Integrative Conference on Health, Life and Social Sciences (ICHLaS 2017)
PB  - Atlantis Press
SN  - 2468-5739
UR  - https://doi.org/10.2991/ichlas-17.2017.17
DO  - https://doi.org/10.2991/ichlas-17.2017.17
ID  - Firdausi2017/12
ER  -