Cartilage Glycoprotein-39 in Patients with Osteoarthritis in Combination with Cardiovascular Pathology

DOI

10.2991/ichw-19.2019.40How to use a DOI?

Keywords

glycoprotein, osteoarthritis, cardiovascular pathology

Abstract

The article studies lipid parameters and inflammatory markers of OA without comorbidity, OA in combination with IHD, AH in conjunction with clinical symptoms of the disease. 110 patients with OA combined with IHD, AH, 30 patients with OA without comorbidity treated at the rheumatology department of the NOSMA clinics, and 30 healthy volunteers of identical gender and age were examined. The clinical parameters of gonarthritis, CGP-39, CRP, ESR, lipid profile (cholesterol, LDL, HDL, triglycerides, CA), and UDE results were analyzed. A significant increase in CGP-39 was observed in all the patients. The highest rates of CGP-39 were found in patients with the third stage of gonarthritis. Reliable direct correlations were found between CGP-39 and clinical indices of gonarthritis severity, CCA IMC thickness, the lipid spectrum, CRP, and ESR. CGP-39 can reflect OA severity. It can be regarded as a risk factor for OA and atherosclerosis development.

Copyright

© 2019, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - A.A. Ktsoeva
AU  - A.S. Medoeva
AU  - I.N. Totrov
AU  - M.S. Khestanova
AU  - M.M. Tebloev
AU  - A.B. Kusova
AU  - Z.T. Tsabolova
PY  - 2019/10
DA  - 2019/10
TI  - Cartilage Glycoprotein-39 in Patients with Osteoarthritis in Combination with Cardiovascular Pathology
BT  - Proceedings of the International Conference on Health and Well-Being in Modern Society (ICHW 2019)
PB  - Atlantis Press
SP  - 167
EP  - 173
SN  - 2468-5739
UR  - https://doi.org/10.2991/ichw-19.2019.40
DO  - 10.2991/ichw-19.2019.40
ID  - Ktsoeva2019/10
ER  -