The Stiffness of Virus Shell: Influenza Lipid Shell

DOI

10.2991/assehr.k.211222.016How to use a DOI?

Keywords

virus shell; stiffness; Michell equation; plate & shell theory; FEA

Abstract

Virus is an infectious agent with microscopic size, a protective shell containing capsomere with protein material called a capsid, and the addition of a shell containing fat called a lipid coat. The one characteristic of a virus is about the shell stiffness, so the virus shell can be assumed as a spring. The value of stiffness of the virus shell is different for various viruses, depending on intrinsic properties (modulus of elasticity) and extrinsic properties (radius and thickness of the virus shell).

In this paper, we analyze the value of stiffness of the virus shell by analytical and simulation. The analytical method is based on plate and shell theory and Michell solution. The other, the simulation is based on finite element analysis (FEA) method. For influenza lipid shell, we find that the stiffness value of the shell based on plate and shell theory is 0.0236 nNnm. Based on Michell solution, the stiffness value of the shell is 0.0225 nNnm. Also, the stiffness value of influenza lipid by FEA method is 0.0227 ± 0.0002 nNnm. Generally, based on the graph that the stiffness value of influenza lipid shell by analytical and simulation is approaching same.

Copyright

© 2021 The Authors. Published by Atlantis Press SARL.

Open Access

This is an open access article under the CC BY-NC license.

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TY  - CONF
AU  - M.R. Fauzi
AU  - Nurfa Risha
AU  - Gede Aris Gunadi
AU  - Luh Putu Budi Yasmini
PY  - 2021
DA  - 2021/12/21
TI  - The Stiffness of Virus Shell: Influenza Lipid Shell
BT  - Proceedings of the 4th International Conference on Innovative Research Across Disciplines (ICIRAD 2021)
PB  - Atlantis Press
SP  - 110
EP  - 115
SN  - 2352-5398
UR  - https://doi.org/10.2991/assehr.k.211222.016
DO  - 10.2991/assehr.k.211222.016
ID  - Fauzi2021
ER  -