Immune-Enhancing Effect of Kombucha on Cyclophosphamide-induced Immunosuppressive Mice

DOI

10.2991/icmcm-16.2016.114How to use a DOI?

Keywords

Kombucha; Cyclophosphamide; Immune-Enhancing activity

Abstract

The purpose of the present study was to investigate the immune-enhancing activity of Kombucha. In immunosuppression experiment, the immune-enhancing effect of Kombucha in immunosuppressive mice was performed.It was showed that Kombucha at high and medium doses doses was able to overcome the CY-induced immunosuppression, significantly improves the body weight, the count of white blood cell, increases the thymus and spleen indices, enhances lymphocyte proliferation activity and peritoneal macrophage function, improves natural killer cells activity compared with negative control group. In addition, the different dose of Kombucha could significantly enhance the activity of alkaline phosphatase (AKP), superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-PX) in blood serum. Therefore, the Kombucha could be an effective immunomodulatory agent.

Copyright

© 2016, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Chunlong Wang
AU  - Mengying Xu
AU  - Shan Gao
AU  - Tianchen Wu
AU  - Chengguang Qin
AU  - Zesheng Zhang
PY  - 2016/12
DA  - 2016/12
TI  - Immune-Enhancing Effect of Kombucha on Cyclophosphamide-induced Immunosuppressive Mice
BT  - Proceedings of the 2016 7th International Conference on Mechatronics, Control and Materials (ICMCM 2016)
PB  - Atlantis Press
SP  - 604
EP  - 612
SN  - 2352-5401
UR  - https://doi.org/10.2991/icmcm-16.2016.114
DO  - 10.2991/icmcm-16.2016.114
ID  - Wang2016/12
ER  -