Proceedings of the 1st International Conference in One Health (ICOH 2017)

Vitamin E Changes Erythrocyte and Leukocyte Levels in Male Rats (Mus Musculus) Due to Strenuous Exercise

Authors
Sugiharto Sugiharto, Mohammad Arif Ali, Anies Setiowati
Corresponding Author
Sugiharto Sugiharto
Available Online July 2017.
DOI
https://doi.org/10.2991/icoh-17.2018.15How to use a DOI?
Keywords
antioxidant, strenuous exercise, blood parameters
Abstract
Oxidative stress can be induced by strenuous exercise either in human or in animal, it can damages erythrocyte during and post-exercise. Furthermore, maximum exercise also affecting leukocyte level. In another hand that vitamin E as an agent of antioxidant might be potentially can be a protector for damage erythrocyte and leukocyte caused by strenuous exercise. The purpose of this study was to investigate effects of vitamin E 0.2 mg and 0.4 mg on the change of erythrocyte and leukocyte levels in male rats (mus musculus) due to strenuous exercise for twenty eight days. Randomized post-test controlled group design was used in this study. Twenty male rats (2-4 months old) were divided into four groups: 1) Control Group (G1); 2) Strenuous Exercise Group (G2); 3) Strenuous Exercise Group + 0.2 mg of vitamin E (G3); 4) Strenuous Exercise Group + 0.4 mg of vitamin E (G4). Strenuous exercise had given every day for 28 days. One-way ANOVA and Post Hoc Tukey was performed to analyze the data. The results showed that the erythrocyte level of strenuous exercise group (G2) was lowest compared to G1, G3, and G4 (P < .05) as well as the leukocyte level as the P-value < .05. The conclusion is the treatment of vitamin E is able to prevent the damage of erythrocyte and to maintain the steady level of leukocyte due to strenuous.
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This is an open access article distributed under the CC BY-NC license.

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Proceedings
Part of series
Advances in Health Sciences Research
Publication Date
July 2017
ISBN
978-94-6252-481-1
ISSN
2468-5739
DOI
https://doi.org/10.2991/icoh-17.2018.15How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - CONF
AU  - Sugiharto Sugiharto
AU  - Mohammad Arif Ali
AU  - Anies Setiowati
PY  - 2017/07
DA  - 2017/07
TI  - Vitamin E Changes Erythrocyte and Leukocyte Levels in Male Rats (Mus Musculus) Due to Strenuous Exercise
PB  - Atlantis Press
SP  - 69
EP  - 74
SN  - 2468-5739
UR  - https://doi.org/10.2991/icoh-17.2018.15
DO  - https://doi.org/10.2991/icoh-17.2018.15
ID  - Sugiharto2017/07
ER  -