Proceedings of the 1st International Conference in One Health (ICOH 2017)

Effectivity 0f Both KIO3 And KI Salt Toward Iodium (I2) Level In Urine, Malondialdehyde (MDA) and Histipathology of Thyroid Gland of Goitrogenic Rats

Authors
Chanif Mahdi, Risman Heli, Sasangka Prasetyawan
Corresponding Author
Chanif Mahdi
Available Online July 2017.
DOI
https://doi.org/10.2991/icoh-17.2018.19How to use a DOI?
Keywords
Goitrogenic, Iodium, Malondialdehyde, KIO3 and KI salt therapy.
Abstract
Goitrogenic a substance that can inhibit the taking of iodine by the thyroid gland, so that the concentration of iodine in the thyroid to be low., is characterized by the inflammation in the gland thyroid area caused an excessive of free radicals. An excessive of free radicals in the body cause oxidative stress, That increasing the levels of malondialdehyde (MDA) as an indicator of lipid peroxidation and decreased levels of urinary iodine excretion levels (EIU). The treated to give KIO3 and KI salt was intended to determine the level of supplementation of iodine (I2), the level of MDA in serum and histological rat thyroid gland. MDA levels are determined through a TBA test (Thio Barbituric acid), meanwhile the histological of the rat thyroid gland was determined by Hematoxylen-Eosin staining (HE). The results showed the KIO3 and KI salt was significantly (p<0.01) reduce levels of MDA in the serum of treatment with KIO3 salt (33.62%) and KI salt (37,02%) and improving histological of the thyroid gland rats.
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Proceedings
Part of series
Advances in Health Sciences Research
Publication Date
July 2017
ISBN
978-94-6252-481-1
ISSN
2468-5739
DOI
https://doi.org/10.2991/icoh-17.2018.19How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - CONF
AU  - Chanif Mahdi
AU  - Risman Heli
AU  - Sasangka Prasetyawan
PY  - 2017/07
DA  - 2017/07
TI  - Effectivity 0f Both KIO3 And KI Salt Toward Iodium (I2) Level In Urine, Malondialdehyde (MDA) and Histipathology of Thyroid Gland of Goitrogenic Rats
PB  - Atlantis Press
SP  - 89
EP  - 98
SN  - 2468-5739
UR  - https://doi.org/10.2991/icoh-17.2018.19
DO  - https://doi.org/10.2991/icoh-17.2018.19
ID  - Mahdi2017/07
ER  -