Effectivity 0f Both KIO3 And KI Salt Toward Iodium (I2) Level In Urine, Malondialdehyde (MDA) and Histipathology of Thyroid Gland of Goitrogenic Rats
Chanif Mahdi, Risman Heli, Sasangka Prasetyawan
Available Online July 2017.
- https://doi.org/10.2991/icoh-17.2018.19How to use a DOI?
- Goitrogenic, Iodium, Malondialdehyde, KIO3 and KI salt therapy.
- Goitrogenic a substance that can inhibit the taking of iodine by the thyroid gland, so that the concentration of iodine in the thyroid to be low., is characterized by the inflammation in the gland thyroid area caused an excessive of free radicals. An excessive of free radicals in the body cause oxidative stress, That increasing the levels of malondialdehyde (MDA) as an indicator of lipid peroxidation and decreased levels of urinary iodine excretion levels (EIU). The treated to give KIO3 and KI salt was intended to determine the level of supplementation of iodine (I2), the level of MDA in serum and histological rat thyroid gland. MDA levels are determined through a TBA test (Thio Barbituric acid), meanwhile the histological of the rat thyroid gland was determined by Hematoxylen-Eosin staining (HE). The results showed the KIO3 and KI salt was significantly (p<0.01) reduce levels of MDA in the serum of treatment with KIO3 salt (33.62%) and KI salt (37,02%) and improving histological of the thyroid gland rats.
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Cite this article
TY - CONF AU - Chanif Mahdi AU - Risman Heli AU - Sasangka Prasetyawan PY - 2017/07 DA - 2017/07 TI - Effectivity 0f Both KIO3 And KI Salt Toward Iodium (I2) Level In Urine, Malondialdehyde (MDA) and Histipathology of Thyroid Gland of Goitrogenic Rats PB - Atlantis Press SP - 89 EP - 98 SN - 2468-5739 UR - https://doi.org/10.2991/icoh-17.2018.19 DO - https://doi.org/10.2991/icoh-17.2018.19 ID - Mahdi2017/07 ER -