Immunogenic Proteins from Salivary Gland of Potential Malaria Vector An. vagus and An. sundaicus

Ika Wahyuni; Rike Oktarianti; Syubbanul Wathon; Lailly Nur Uswatul Hasanah; Kartika Senjarini

doi:10.2991/978-94-6463-062-6_35

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Immunogenic Proteins from Salivary Gland of Potential Malaria Vector An. vagus and An. sundaicus

Authors

Ika Wahyuni¹, Rike Oktarianti¹, Syubbanul Wathon¹, Lailly Nur Uswatul Hasanah¹, Kartika Senjarini¹^{, *}

¹Department of Biology, Faculty of Mathematics and Natural Sciences, University of Jember, Jember, Indonesia

^*Corresponding author. Email: senjarini@unej.ac.id

Corresponding Author

Kartika Senjarini

Available Online 22 December 2022.

DOI: 10.2991/978-94-6463-062-6_35 How to use a DOI?
Keywords: Immunogenic proteins; salivary gland; vector; Anopheles; Malaria
Abstract: The salivary gland proteins of the Anopheles (An.) female mosquito play vital roles in the transmission of Plasmodium into the human host. A comprehensive understanding of Anopheles identity and its related salivary proteins is a key for vector-based malaria control. This research aims to analyse the protein profile and immunogenicity of Anopheles salivary gland proteins from 2 potential Anopheles vectors, An. vagus and An. sundaicus. Female Anopheles are collected from Bangsring village, Banyuwangi Regency by direct-landing collection. Each species are identified by morphological features and internal transcribed spacer 2 (ITS2). Immunogenic proteins were determined by Western Blotting with IgG from people living in the endemic area as primary antibodies. Immunoblotting results showed the presence of 3 immunogenic protein bands with a molecular weight of 34, 46, and 66 kDa in both species. Furthermore, the 99 kDa protein band was present merely in An. sundaicus. Moreover, the result showed that two distinct species have different profiles and immunogenic proteins.
Copyright: © 2023 The Author(s)
Open Access: Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title: Proceedings of the 4th International Conference on Life Sciences and Biotechnology (ICOLIB 2021)
Series: Advances in Biological Sciences Research
Publication Date: 22 December 2022
ISBN: 10.2991/978-94-6463-062-6_35
ISSN: 2468-5747
DOI: 10.2991/978-94-6463-062-6_35 How to use a DOI?
Open Access: Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

ris enw bib

TY  - CONF
AU  - Ika Wahyuni
AU  - Rike Oktarianti
AU  - Syubbanul Wathon
AU  - Lailly Nur Uswatul Hasanah
AU  - Kartika Senjarini
PY  - 2022
DA  - 2022/12/22
TI  - Immunogenic Proteins from Salivary Gland of Potential Malaria Vector An. vagus and An. sundaicus
BT  - Proceedings of the 4th International Conference on Life Sciences and Biotechnology (ICOLIB 2021)
PB  - Atlantis Press
SP  - 354
EP  - 362
SN  - 2468-5747
UR  - https://doi.org/10.2991/978-94-6463-062-6_35
DO  - 10.2991/978-94-6463-062-6_35
ID  - Wahyuni2022
ER  -

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