This study evaluated the effects of Curcuma zedoaria extract on blood glucose, Placental Growth Factor (PlGF), and kidney histopathology in diabetic nephropathy (DN) Wistar rats. DN, a severe diabetic complication, leads to progressive kidney damage. Using a post-test-only control group design, diabetes...

Shamandar, or beetroot (Beta vulgaris L.), is a member of the Amaranthaceae family. It has been used as a kidney protector, emmenagogue, carminative, hemostatic, and cardiovascular protector. Extracts from Beta vulgaris L. roots have been shown to have hepatoprotective, antihypertensive, hypoglycemic,...

This study investigates the potential of Vitex trifolia (legundi) extract to reduce resistance to radiation and chemotherapy in epithelial cancer by targeting the Bcl-2 apoptosis pathway. The objectives include (1) characterizing Casticin and Labdane-Type Diterpene compounds; (2) analyzing Bcl-2 gene...

Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by insulin resistance and chronic hyperglycemia. Low adiponectin levels are associated with increased T2DM risk. Andaliman, with its antioxidant and anti-inflammatory properties, may influence adiponectin levels and improve insulin...

This study explores the role of bioactive compounds from Paraboea leuserensis in enhancing vascular endothelial growth factor expression, a critical factor in wound healing. Using liquid chromatography-tandem mass spectrometry, compounds such as quercetin, kaempferol, ellagic acid, myricetin, and betaine...

The Body weight is body mass which is usually used to measure a person’s nutritional status. Each person’s ideal body weight varies according to race, ethnicity, gender, age, and socioeconomic status. According to the World Health Organization (WHO), in 2014 more than 1.9 billion adults aged more than...

Sunkist orange and lime peels contain flavonoids with strong antioxidant properties, capable of preventing lipid oxidation and neutralizing free radicals. These antioxidants are promising for addressing pancreatic cell damage in diabetes, which is often caused by oxidative stress. This study evaluated...

The administration of a high-fat creamer will cause hyper-lipidemia, an atherosclerosis risk factor. If atherosclerosis occurs in the renal arteries, it can cause impaired kidney function. Inulin, a prebiotic, can be used as a creamer ingredient to produce a low-fat creamer. This study aims to determine...

Diabetes Mellitus is a globally prevalent metabolic disease, with cases rising yearly. Currently, approximately 171 million individuals worldwide are affected, and projections suggest this will reach 366 million by 2030. Among them, 15–20% experience diabetic foot ulcers, with around 15% of these cases...

Diabetes Mellitus (DM) is a chronic metabolic disease with many causes and is characterized by elevated blood sugar levels caused by failure of insulin secretion or insulin action. Many plant secondary metabolite compounds can be used as medicine. Kersen Leaves (Muntingia Calabura L.) have secondary...

Skin infections caused by Staphylococcus aureus, Propionibacterium acnes, Candida albicans, and Malassezia furfur are prevalent in tropical regions, aggravated by antimicrobial resistance. This study explores the antimicrobial potential of ethanol extracts of palm oil (Elaeis guineensis) leaves, as a...

This study evaluated the effects of Curcuma zedoaria extract on blood glucose, Placental Growth Factor (PlGF), and kidney histopathology in diabetic nephropathy (DN) Wistar rats. DN, a severe diabetic complication, leads to progressive kidney damage. Using a post-test-only control group design, diabetes...

Diabetes Mellitus is characterized by impaired insulin secretion or impaired insulin function (insulin resistance) in the liver and muscles. The liver is one of the largest organs in the body and the center of metabolism in the body. The study aims to determine the effect of Andrographis paniculata leaf...