Proceedings of the 2nd International Conference on Lifestyle Diseases and Natural Medicine (ICOLIFEMED 2025)

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Exploration and Characterization of Natural Antioxidant Compounds from Leea aequata L. Leaves through In Vitro Evaluation

Authors
Roy Indrianto Bangar1, *, Gita Saraswati1, Loice Desy Krisna Yanti Waruwu1
1Department of Clinical Pharmacy, Faculty of Medicine, Dentistry and Health Sciences, Universitas Prima Indonesia, Medan, 20118, Indonesia
*Corresponding author. Email: royindriantobangars@unprimdn.ac.id
Corresponding Author
Roy Indrianto Bangar
Available Online 2 January 2026.
DOI
10.2991/978-94-6463-962-9_31How to use a DOI?
Keywords
Leea aequata; antioxidant activity; DPPH assay; flavonoids; natural antioxidants
Abstract

This study explores the antioxidant potential of Leea aequata L. leaves through in vitro evaluation to identify and characterize bioactive compounds responsible for its antioxidant activity. The leaves were extracted, fractionated, and purified, and the antioxidant capacity was assessed using the DPPH assay. The ethyl acetate fraction exhibited the strongest activity with an IC 50 value of 11.309 ppm. Further purification using preparative thin-layer chromatography (TLC) isolated a flavonoid compound that demonstrated notable antioxidant potential with an IC 50 value of 26.646 ppm. These findings confirm the role of flavonoids as major contributors to the antioxidant properties of Leea aequata L. and support its potential as a natural source of therapeutic antioxidants. This research provides scientific validation for the traditional use of Leea aequata and contributes to the broader understanding of plant-based antioxidants as sustainable health agents.

Copyright
© 2025 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the 2nd International Conference on Lifestyle Diseases and Natural Medicine (ICOLIFEMED 2025)
Series
Advances in Health Sciences Research
Publication Date
2 January 2026
ISBN
978-94-6463-962-9
ISSN
2468-5739
DOI
10.2991/978-94-6463-962-9_31How to use a DOI?
Copyright
© 2025 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

risenwbib
TY  - CONF
AU  - Roy Indrianto Bangar
AU  - Gita Saraswati
AU  - Loice Desy Krisna Yanti Waruwu
PY  - 2026
DA  - 2026/01/02
TI  - Exploration and Characterization of Natural Antioxidant Compounds from Leea aequata L. Leaves through In Vitro Evaluation
BT  - Proceedings of the 2nd International Conference on Lifestyle Diseases and Natural Medicine (ICOLIFEMED 2025)
PB  - Atlantis Press
SP  - 310
EP  - 321
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6463-962-9_31
DO  - 10.2991/978-94-6463-962-9_31
ID  - Bangar2026
ER  -