Quantitative detection of MMP-2 and relationship of the clinical features and prognosis of lung cancer

DOI

10.2991/icsste-15.2015.54How to use a DOI?

Keywords

lung cancer, MMP-2, gene expression, invasion and metastasis, flow cytometry.

Abstract

Objective is to discuss (MMP-2) relationship of matrix metalloproteinase-2 and lung cancer invasion, metastasis and prognosis. Methods: use flow immunoassay for the quantitative detection of MMP-2 expression in 28 cases of benign lung lesions and 78 cases of lung cancer. Results: MMP 2-expression promotes lung cancer is higher than benign lesions (p <0.05), and there is a significant correlation (p <0.05) of lung cancer clinical stage and histological grade. Conclusion: The high expression of MMP-2 promotes the invasion and metastasis of lung cancer is, the higher the value is, the higher the clinical stage is, and the lower the tissue differentiation is, suggesting that MMP-2 not only can be used as indicators of lung cancer, but also is effective prognosis.

Copyright

© 2015, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Ma Jie
AU  - Peng Haiyuan
AU  - Peng Haiping
AU  - Zhu Huifang
PY  - 2015/04
DA  - 2015/04
TI  - Quantitative detection of MMP-2 and relationship of the clinical features and prognosis of lung cancer
BT  - Proceedings of the 2015 International Conference on Social Science and Technology Education
PB  - Atlantis Press
SP  - 183
EP  - 185
SN  - 2352-5398
UR  - https://doi.org/10.2991/icsste-15.2015.54
DO  - 10.2991/icsste-15.2015.54
ID  - Jie2015/04
ER  -