Proceedings of the International Dental Conference of Sumatera Utara 2017 (IDCSU 2017)

Effectivity of Lime Peel Decoction (Citrus Aurantifolia Swingle) on Osteoblast and Osteoclast Numbers in the Process of Bone Healing Post-Extraction on White Rat (Rattus Norvegicus) Wistar Strain

Authors
Azimah Nurin Nafilah, Nurul Istichomah
Corresponding Author
Azimah Nurin Nafilah
Available Online February 2018.
DOI
https://doi.org/10.2991/idcsu-17.2018.14How to use a DOI?
Keywords
Decoction of lime peel (Citrus aurantifolia Swingle, osteoblast, osteoclast, denture, remodeling
Abstract
Prolong teeth loss due to dental extraction causes interference with the Temporomandibular Joint (TMJ), speech impairment and psychological aspects of aesthetics. For the fulfillment of general, dental and oral health, denture is needed to maintain necessary function of chewing. Generally, after tooth extraction, the patient will inquire the duration needed for denture fabrication, because the bone healing process takes a long time, so the denture fabrication is delayed. The current solution is the usage of chemical drugs to cope with injuries which have side effects, it is necessary to innovate the development of herbal medicine that can accelerate healing of bones. Potential herbal remedies include lime peel decoction (Citrus aurantifolia Swingle). Post-extraction wound healing consists of inflammatory stage, repair stage, and remodeling stage. For denture fabrication, the socket or periodontal tissue must go through the remodeling phase to obtain strong and retentive bone support. Remodeling phase indicators include osteoblasts and osteoclasts. The bone will undergo continuously dynamic process of remodeling, where osteoblasts play a role in formation and osteoclasts in resorption. Citrus aurantifolia Swingle contains flavonoid and vitamin C can inhibit differentiation of osteoclasts so as to have an effect on increasing number of osteoblasts and accelerate the occurrence of bone healing. The extracted lime peel decoction was given to white rat (Rattus norvegicus) for 21 days and observes osteoblast and osteoclast cells. Lime peel decoction (Citrus aurantifolia Swingle) is effective towards post-extraction bone healing in white rats (Rattus norvegicus) wistar strains.
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Proceedings
International Dental Conference of Sumatera Utara 2017 (IDCSU 2017)
Part of series
Advances in Health Sciences Research
Publication Date
February 2018
ISBN
978-94-6252-474-3
ISSN
2468-5739
DOI
https://doi.org/10.2991/idcsu-17.2018.14How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - CONF
AU  - Azimah Nurin Nafilah
AU  - Nurul Istichomah
PY  - 2018/02
DA  - 2018/02
TI  - Effectivity of Lime Peel Decoction (Citrus Aurantifolia Swingle) on Osteoblast and Osteoclast Numbers in the Process of Bone Healing Post-Extraction on White Rat (Rattus Norvegicus) Wistar Strain
BT  - International Dental Conference of Sumatera Utara 2017 (IDCSU 2017)
PB  - Atlantis Press
SN  - 2468-5739
UR  - https://doi.org/10.2991/idcsu-17.2018.14
DO  - https://doi.org/10.2991/idcsu-17.2018.14
ID  - NurinNafilah2018/02
ER  -