Proceedings of the International Dental Conference of Sumatera Utara 2017 (IDCSU 2017)

sIgA and Lisozim as Biomarker of Early Childhood Caries Risk

Authors
Essie Octiara, Heriandi Sutadi, Yahwardiah Siregar, Ameta Primasari
Corresponding Author
Essie Octiara
Available Online February 2018.
DOI
https://doi.org/10.2991/idcsu-17.2018.26How to use a DOI?
Keywords
ECC, sIgA, salivary lysozyme, biomarker
Abstract
Caries in children under 6 years old (Early Childhood Caries) is still a major oral health problems in many countries. The high prevalence of ECC should be prevented immediately based on the cause of caries. Saliva is one of the factors that play role in dental caries process, also play a role as caries prevention. This article describes the relationship between sIgA and salivary lysozyme to the incidence of ECC and the development of that protein as one of the caries biomarkers. Several studies reported that sIgA in caries-free children had higher concentrations than in ECC children. Lysozyme concentrations in unstimulated saliva are also significantly higher in the caries-free group compared with the ECC group. Determination of lysozyme and sIgA level in saliva may be helpful in diagnosing caries diseases and infections. It is concluded that the development of sIgA and salivary lysozyme can be used as one of the biomarkers for dental caries detection, risk assessment, diagnosis, prognosis and disease monitoring, and evaluation in ECC.
Open Access
This is an open access article distributed under the CC BY-NC license.

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Proceedings
International Dental Conference of Sumatera Utara 2017 (IDCSU 2017)
Part of series
Advances in Health Sciences Research
Publication Date
February 2018
ISBN
978-94-6252-474-3
ISSN
2468-5739
DOI
https://doi.org/10.2991/idcsu-17.2018.26How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - CONF
AU  - Essie Octiara
AU  - Heriandi Sutadi
AU  - Yahwardiah Siregar
AU  - Ameta Primasari
PY  - 2018/02
DA  - 2018/02
TI  - sIgA and Lisozim as Biomarker of Early Childhood Caries Risk
BT  - International Dental Conference of Sumatera Utara 2017 (IDCSU 2017)
PB  - Atlantis Press
SN  - 2468-5739
UR  - https://doi.org/10.2991/idcsu-17.2018.26
DO  - https://doi.org/10.2991/idcsu-17.2018.26
ID  - Octiara2018/02
ER  -