Proceedings of the 2025 2nd International Symposium on Agricultural Engineering and Biology (ISAEB 2025)

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Research on Functions of Non-coding Small RNA in Germ Cells of Mammals

Authors
Yihan Liu1, *
1Jinan Foreign Language School International Centre, Jinan, 250031, China
*Corresponding author. Email: 16653179119@163.com
Corresponding Author
Yihan Liu
Available Online 15 December 2025.
DOI
10.2991/978-94-6463-910-0_16How to use a DOI?
Keywords
mammals; non-coding small RNA; germ cells
Abstract

Non-coding small RNA (ncRNA) is a kind of short-chain RNA which has important functions in gene expression regulation, mainly including miRNA, siRNA and piRNA. They play the critical role in proliferation, differentiation and genome stability maintenance of germ cells of mammals through multiple mechanisms. miRNA participates in regulation of follicular development, steroidogenesis and sperm meiosis. siRNA affects maturity of oocytes by disturbing transposons and regulating microtubule kinetics. piRNA has unique functions in regulation of transposons silence and germ cell expressions. In this study, the biosynthesis of ncRNA in egg cells and sperm cells of mammals as well as its functional mechanism was reviewed systematically. Moreover, research progresses on ncRNA in germ cell development, gene expression regulation and disease development were summarized. A deep understanding on the role of ncRNA in reproductive system is not only conducive to disclose the molecular basis determined by reproductive cell fate, but also can provide new research directions and theoretical references to treat reproductive-related diseases like male infertility.

Copyright
© 2025 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the 2025 2nd International Symposium on Agricultural Engineering and Biology (ISAEB 2025)
Series
Advances in Biological Sciences Research
Publication Date
15 December 2025
ISBN
978-94-6463-910-0
ISSN
2468-5747
DOI
10.2991/978-94-6463-910-0_16How to use a DOI?
Copyright
© 2025 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

risenwbib
TY  - CONF
AU  - Yihan Liu
PY  - 2025
DA  - 2025/12/15
TI  - Research on Functions of Non-coding Small RNA in Germ Cells of Mammals
BT  - Proceedings of the 2025 2nd International Symposium on Agricultural Engineering and Biology (ISAEB 2025)
PB  - Atlantis Press
SP  - 150
EP  - 157
SN  - 2468-5747
UR  - https://doi.org/10.2991/978-94-6463-910-0_16
DO  - 10.2991/978-94-6463-910-0_16
ID  - Liu2025
ER  -