Phenotypic effects of polymorphism of the calpastatin gene (CAST), associated with growth and development indicators, in West Siberian mutton breed

DOI

10.2991/ispc-19.2019.26How to use a DOI?

Keywords

West Siberian mutton breed, sheep, genes, calpastatin, live weight

Abstract

One of the modern ways to improve the breeding qualities is selection using the genetic markers or the marker-assisted selection. At the present stage of animal breeding development, and sheep breeding in particular, marker-assisted selection methods have high practical application, which is based on identifying the interrelation of genes with productivity indicators. Genetic markers associated with growth and meat productivity indicators have been identified, one of which is the CAST gene (calpastatin). The purpose of our research was to study the phenotypic effect of the polymorphism of the CAST gene, associated with growth and development indicators, in sheep of the West Siberian mutton breed. The frequency of the occurrence of alleles and genotypes of the CAST gene was detected by PCR analysis in stud rams (n = 30) and ewes (n = 70) of the West Siberian mutton breed. It has been established that the most frequent genotype in the population of sheep of West Siberian mutton breed is the MM genotype, the frequency of which reaches 0.710 or 72%, the alternative CAST NN genotype is found in singular animals – 5%. Sheep with the CAST MN genotype were distinguished by the best average daily weight gain from birth to weaning by 6.9% and live weight by 20% (P <0.01), in relation to the sheep with genotype NN. There were no significant differences in growth and development indicators between the MM and MN genotypes.

Copyright

© 2019, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Antonina Afanasyeva
AU  - Vladislav Sarychev
AU  - Galina Goncharenko
PY  - 2019/06
DA  - 2019/06
TI  - Phenotypic effects of polymorphism of the calpastatin gene (CAST), associated with growth and development indicators, in West Siberian mutton breed
BT  - Proceedings of the International Scientific and Practical Conference “Digital agriculture - development strategy” (ISPC 2019)
PB  - Atlantis Press
SP  - 116
EP  - 120
SN  - 1951-6851
UR  - https://doi.org/10.2991/ispc-19.2019.26
DO  - 10.2991/ispc-19.2019.26
ID  - Afanasyeva2019/06
ER  -