Proceedings of the 9th International Seminar on Tropical Animal Production (ISTAP 2021)

The Potency of Leptin Gene as a Selection Marker of Economic Traits for Madura Cattle: Preliminary Study

Authors
Tristianto Nugroho1, Tri Satya Mastuti Widi1, Dyah Maharani1, *
1Faculty of Animal Science, Universitas Gadjah Mada, Indonesia
*Corresponding author. Email: d.maharani@ugm.ac.id
Corresponding Author
Dyah Maharani
Available Online 24 February 2022.
DOI
10.2991/absr.k.220207.048How to use a DOI?
Keywords
Leptin Gene; Selection Marker; Madura Cattle; Economic Trait
Abstract

The Leptin gene, also known as ‘obese’, was an important regulator of growth traits which is the principal economic value of beef cattle. This paper aimed to investigate the potency of the Leptin gene as a selection marker of economic traits for Madura cattle. This study was performed by literature review from published studies. First, publications were collected to obtain a Leptin genes study on Madura cattle and Indonesian Cattle. Next, association study publications were collected to obtain Leptin gene polymorphism and its effect on the economic traits of various cattle. The selected economic traits were growth, carcass, milk, and reproduction. In total, 26 papers were used in this study. As a results, we found Leptin gene studies on nine Indonesian local cattle, including Madura, Kebumen Ongole Grade, Ongole Grade, Sumba Ongole, Bali, Pasundan, Bali Cross, Pesisir and Ciamis Local Cattle. However, most of this study is limited to polymorphism identification. Exon 2, Intron 2, and Exon 3 of the Leptin gene polymorphism were associated with four selected economic traits on several loci. However, Leptin gene SNP g.1180C>T (also referred to as R25C, Arg25Cys, 1047C>T, C305T, R4C, C73T, and LepKpn2I) in exon 2 was known to had association with growth, carcass, milk, and reproduction trait. It was concluded that SNP g.1180C>T had the potency to be used as a selection marker of economic traits for Madura cattle. Following marker selection, an association study on Madura Cattle was further to validate this result.

Copyright
© 2022 The Authors. Published by Atlantis Press International B.V.
Open Access
This is an open access article under the CC BY-NC license.

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Volume Title
Proceedings of the 9th International Seminar on Tropical Animal Production (ISTAP 2021)
Series
Advances in Biological Sciences Research
Publication Date
24 February 2022
ISBN
10.2991/absr.k.220207.048
ISSN
2468-5747
DOI
10.2991/absr.k.220207.048How to use a DOI?
Copyright
© 2022 The Authors. Published by Atlantis Press International B.V.
Open Access
This is an open access article under the CC BY-NC license.

Cite this article

TY  - CONF
AU  - Tristianto Nugroho
AU  - Tri Satya Mastuti Widi
AU  - Dyah Maharani
PY  - 2022
DA  - 2022/02/24
TI  - The Potency of Leptin Gene as a Selection Marker of Economic Traits for Madura Cattle: Preliminary Study
BT  - Proceedings of the 9th International Seminar on Tropical Animal Production (ISTAP 2021)
PB  - Atlantis Press
SP  - 231
EP  - 237
SN  - 2468-5747
UR  - https://doi.org/10.2991/absr.k.220207.048
DO  - 10.2991/absr.k.220207.048
ID  - Nugroho2022
ER  -