Proceedings of the 3rd KOBI Congress, International and National Conferences (KOBICINC 2020)

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The Circulating Level of IL-1β in Patients with Age-related Macular Degeneration (AMD) in Yogyakarta: Characteristics to Disease Activity

Authors
Supanji, Ayudha Bahana Ilham Perdamaian, Anindita Dianratri, Muhammad Eko Prayogo, Muhammad Bayu Sasongko, Firman Setya Wardhana, Tri Wahyu Widayanti, Angela Nurini Agni, Chio Oka
Corresponding Author
Supanji
Available Online 23 June 2021.
DOI
10.2991/absr.k.210621.073How to use a DOI?
Keywords
Age-related macular degeneration, inflammation, inflammatory cytokines
Abstract

Age-related Macular Degeneration (AMD) is leading factors for blindness and impaired visual acuity in developed countries. It is importance to study the dynamic of cytokines concentration during the exudative event of AMD to contribute in the future drugs inventions. This research aims to investigate the IL-1β profiles in plasma of exudative AMD patients. In this cross-sectional study, blood plasma samples from 17 AMD patients and 23 age-matched were collected. Samples were examined for IL-1β inflammatory cytokines using a commercially available ELISA. Acquired data were log transformed to normalize the outlier prior student T-test (SPSS software). Based on recent research, there is a statistically difference of IL-1β among AMD patients and control. IL-1 β concentration were higher at control. Detection of high level of inflammatory cytokines supports a role for inflammation in AMD pathogenesis.

Copyright
© 2021, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the 3rd KOBI Congress, International and National Conferences (KOBICINC 2020)
Series
Advances in Biological Sciences Research
Publication Date
23 June 2021
ISBN
10.2991/absr.k.210621.073
ISSN
2468-5747
DOI
10.2991/absr.k.210621.073How to use a DOI?
Copyright
© 2021, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

risenwbib
TY  - CONF
AU  - Supanji
AU  - Ayudha Bahana Ilham Perdamaian
AU  - Anindita Dianratri
AU  - Muhammad Eko Prayogo
AU  - Muhammad Bayu Sasongko
AU  - Firman Setya Wardhana
AU  - Tri Wahyu Widayanti
AU  - Angela Nurini Agni
AU  - Chio Oka
PY  - 2021
DA  - 2021/06/23
TI  - The Circulating Level of IL-1β in Patients with Age-related Macular Degeneration (AMD) in Yogyakarta: Characteristics to Disease Activity
BT  - Proceedings of the 3rd KOBI Congress, International and National Conferences (KOBICINC 2020)
PB  - Atlantis Press
SP  - 434
EP  - 436
SN  - 2468-5747
UR  - https://doi.org/10.2991/absr.k.210621.073
DO  - 10.2991/absr.k.210621.073
ID  - 2021
ER  -