Lipase Catalyzed Naproxen Methyl Ester Enantioselective Hydrolysis in Ionic Liquids
- 10.2991/mcei-16.2016.4How to use a DOI?
- Lipase; Enantioselective hydrolysis; Naproxen; Ionic liquids; Biphasic system
A series of dialkylimidazolium ionic liquids with various anions including hexafluorophosphate alkane sulfonate and tetrafluoroborates were studied in the lipase-catalyzed enantioselective hydrolysis. Lipase activity,stability and enantioselectivity were determined by both of alkane and anions. In the best aqueous- C4mimPF6 biphasic system lipase resolution of Naproxen proceed with much effective. It was observed that the activity of lipase in aqueous- C4mimPF6 system was comparable with that in aqueous-organic system, but the enantiomeric ratio of Lipase-catalysis hydrolysis in aqueous - C4mimPF6 biphasic system (E>300) was much higher than that in aqueous -organic biphasic system (E 90).
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Cite this article
TY - CONF AU - Shengbo Gao AU - Quanhui Li AU - Tingting Yao AU - Zhengyang Wang AU - Luoyun Zheng AU - Jiaying Xin PY - 2016/12 DA - 2016/12 TI - Lipase Catalyzed Naproxen Methyl Ester Enantioselective Hydrolysis in Ionic Liquids BT - Proceedings of the 2016 6th International Conference on Mechatronics, Computer and Education Informationization (MCEI 2016) PB - Atlantis Press SP - 14 EP - 17 SN - 1951-6851 UR - https://doi.org/10.2991/mcei-16.2016.4 DO - 10.2991/mcei-16.2016.4 ID - Gao2016/12 ER -