Proceedings of the 2015 International Conference on Mechanical Science and Engineering

A Comprehensive Data Mining Method of Constructing the Interaction Network of the Microrna Differential Expression

Authors
Rong Wang, Xiaoai Chen, Yafen Chen, Yiwei Wang, Ping Zhou, Guoming Yuan
Corresponding Author
Rong Wang
Available Online March 2016.
DOI
10.2991/mse-15.2016.42How to use a DOI?
Keywords
data mining method; interaction network; microrna; differential expression
Abstract

Objective To analyze the expression of microRNA in Chinese and Italy women by a series of data mining methods to rendering microRNA network. Methods Using T test, Pearson correlation method to deal with the data, Using Cytoscape3.2.1 to draw the interaction network, and do the analysis. Results After the methods, we have found the different microRNAs in expression of breast cancer, and it was found that there were differences in the pathogenesis of breast cancer between the two countries in Italy and China. Conclusion The data mining method designed by this research can be successfully found in the gene expression profile of microRNA in the two countries, the mechanism of breast cancer between different races has been studied.

Copyright
© 2016, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Download article (PDF)

Volume Title
Proceedings of the 2015 International Conference on Mechanical Science and Engineering
Series
Advances in Engineering Research
Publication Date
March 2016
ISBN
10.2991/mse-15.2016.42
ISSN
2352-5401
DOI
10.2991/mse-15.2016.42How to use a DOI?
Copyright
© 2016, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - CONF
AU  - Rong Wang
AU  - Xiaoai Chen
AU  - Yafen Chen
AU  - Yiwei Wang
AU  - Ping Zhou
AU  - Guoming Yuan
PY  - 2016/03
DA  - 2016/03
TI  - A Comprehensive Data Mining Method of Constructing the Interaction Network of the Microrna Differential Expression
BT  - Proceedings of the 2015 International Conference on Mechanical Science and Engineering
PB  - Atlantis Press
SP  - 245
EP  - 250
SN  - 2352-5401
UR  - https://doi.org/10.2991/mse-15.2016.42
DO  - 10.2991/mse-15.2016.42
ID  - Wang2016/03
ER  -