Proceedings of the 2nd Global Health and Innovation in conjunction with 6th ORL Head and Neck Oncology Conference (ORLHN 2021)

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Diagnostic Performance Between White Light Endoscopy and Narrow Band Imaging in Detection of Nasopharyngeal Carcinoma

A Systematic Review and Meta-Analysis

Authors
M.A. Pamuji1, 3, *, B.S.R. Utomo2, L. Marlina2, J.A. Trixie1, L. Tasya1, V.N. Hutagalung1, D.N. Esterini1
1Faculty of Medicine, Universitas Kristen Indonesia, Jakarta, Indonesia
2Department of Otorhinolaryngology, Head and Neck Surgery Faculty of Medicine Universitas Kristen Indonesia, General Hospital of Universitas Kristen Indonesia, Jakarta, Indonesia
3Pamuji MA; Faculty of Medicine, Universitas Kristen Indonesia
*Corresponding author. Email: maurin.asyita@gmail.com
Corresponding Author
M.A. Pamuji
Available Online 21 February 2022.
DOI
10.2991/ahsr.k.220206.011How to use a DOI?
Keywords
Nasopharyngeal Carcinoma; Narrow Band Imaging; White Light Endoscopy
Abstract

Nasopharyngeal Carcinoma (NPC) is an epithelial carcinoma originating from the nasopharynx mucosa lining. It is the most common head and necks malignant globally, especially in Asia. NPC is mostly located in Fossa of Rosenmüller, an area that is hard to observe. To diagnose NPC, radiologic imaging and endoscopic examination are necessary. White Light Endoscopy (WLE) is a basic standard endoscopy examination that can be used to diagnose NPC. On the other hand, many studies were expecting for another examination, Narrow Band Imaging (NBI), to be more sensitive in diagnosing NPC than WLE. This meta-analysis aimed to compare the diagnostic performance between WLE and NBI in NPC detection. A literature search was performed using medical literature databases such as PubMed, BMC, Research Gate, and Medical Journal. The studies that we used were published in 2011-2021. Review Manager 5.4.1 was utilized to analyze data extraction and the risk of bias. Seventeen studies were expecting used in this meta-analysis. All of those studies had fulfilled inclusion criteria. The WLE’s sensitivity was 2-90 % and its specificity was 0-100% (95% CI). Meanwhile, NBI’s sensitivity was 60-100% and its specificity was 0-100% (95% CI). NBI was more sensitive in diagnosing NPC than WLE, but both had the same specificity value. Further studies might be useful to validate this examination.

Copyright
© 2022 The Authors. Published by Atlantis Press International B.V.
Open Access
This is an open access article under the CC BY-NC license.

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Volume Title
Proceedings of the 2nd Global Health and Innovation in conjunction with 6th ORL Head and Neck Oncology Conference (ORLHN 2021)
Series
Advances in Health Sciences Research
Publication Date
21 February 2022
ISBN
10.2991/ahsr.k.220206.011
ISSN
2468-5739
DOI
10.2991/ahsr.k.220206.011How to use a DOI?
Copyright
© 2022 The Authors. Published by Atlantis Press International B.V.
Open Access
This is an open access article under the CC BY-NC license.

Cite this article

risenwbib
TY  - CONF
AU  - M.A. Pamuji
AU  - B.S.R. Utomo
AU  - L. Marlina
AU  - J.A. Trixie
AU  - L. Tasya
AU  - V.N. Hutagalung
AU  - D.N. Esterini
PY  - 2022
DA  - 2022/02/21
TI  - Diagnostic Performance Between White Light Endoscopy and Narrow Band Imaging in Detection of Nasopharyngeal Carcinoma
BT  - Proceedings of the 2nd Global Health and Innovation in conjunction with 6th ORL Head and Neck Oncology Conference (ORLHN 2021)
PB  - Atlantis Press
SP  - 51
EP  - 58
SN  - 2468-5739
UR  - https://doi.org/10.2991/ahsr.k.220206.011
DO  - 10.2991/ahsr.k.220206.011
ID  - Pamuji2022
ER  -