Proceedings of the 19 th Otorhinolaryngology head and neck surgery national congress (PERHATIKL 2022)

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Chemotherapy in the Treatment of Squamous Cell Carcinoma of the Head and Neck

Authors
Ghina Aghniya1, *, Yussy Afriani Dewi1
1Department of Otorhinolaryngology - Head and Neck Surgery, Faculty of Medicine, Padjadjaran University/Hasan Sadikin General Hospital Bandung, Bandung, Indonesia
*Corresponding author.
Corresponding Author
Ghina Aghniya
Available Online 31 October 2023.
DOI
10.2991/978-94-6463-280-4_46How to use a DOI?
Keywords
HNSCCs; Chemotherapy; Cancer
Abstract

Head and neck squamous cell carcinomas (HNSCCs) rank as the sixth most prevalent cancer globally. Despite advancements in combined therapies, the overall survival rate after five years remains approximately 40% to 50%. The burden of HNSCC varied by region and related with exposure to tobacco-deriived carcinogens, excessive alcohol consumption, or both. HNSCC originates from the epithelial cells lining the mucosal surfaces of the oral cavity, pharynx, larynx, and sinonasal tract. The treatment options for patients with head and neck squamous cell carcinoma include surgery, radiation, and chemotherapy, used in different combinations depending on the TNM stage and primary site. Surgery or radiation alone is suitable for resectable tumors with clear margins and preservation of function. Radiation therapy is employed alongside surgery or in combination with chemotherapy for locally advanced disease. As multimodality treatments for HNSCC improve local control, there is a belief that systemic therapy with multiple agents can further enhance distant control and overall survival.

Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the 19 th Otorhinolaryngology head and neck surgery national congress (PERHATIKL 2022)
Series
Advances in Health Sciences Research
Publication Date
31 October 2023
ISBN
10.2991/978-94-6463-280-4_46
ISSN
2468-5739
DOI
10.2991/978-94-6463-280-4_46How to use a DOI?
Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

risenwbib
TY  - CONF
AU  - Ghina Aghniya
AU  - Yussy Afriani Dewi
PY  - 2023
DA  - 2023/10/31
TI  - Chemotherapy in the Treatment of Squamous Cell Carcinoma of the Head and Neck
BT  - Proceedings of the 19 th Otorhinolaryngology head and neck surgery national congress (PERHATIKL 2022)
PB  - Atlantis Press
SP  - 254
EP  - 260
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6463-280-4_46
DO  - 10.2991/978-94-6463-280-4_46
ID  - Aghniya2023
ER  -