The Effect of Concentration Calcium Alginate On Metformine Encapsulated

DOI

10.2991/snk-19.2019.20How to use a DOI?

Keywords

Encapsulation, metformine, Alginate

Abstract

This research aimed to study the effect of concentration calcium alginate on metformine encapsulation processes and investigated characteristic of metformine encapsulation. The encapsulation of metformine performed using chitosan and calcium alginate polymers with calcium chloride as crosslingk agent. The concentration of calcium alginate were variated 0.5%; 1.0%; 1.5%; 2.0%; 2.5%; and 3.0% (w/v). The results showed that the highest encapsulation efficiency of metformine on concentratiton of alginate 2.0% (w/v) and the lowest in the alginate 0% (w/v), respectively by 80.51% and 55.94%. Encapsulation resulted with the highest The spectra FTIR analysis showed that there is vibration in 1497.91 cm-1 that indicated interaction between the carboxyl functional group of alginate and the amine functional group of chitosan

Copyright

© 2019, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Sari Edi Cahyaningrum
AU  - Nuniek Herdyastuti
AU  - Amaria Amaria
AU  - Pupuh Findia
PY  - 2019/12
DA  - 2019/12
TI  - The Effect of Concentration Calcium Alginate On Metformine Encapsulated
BT  - Proceedings of the National Seminar on Chemistry 2019 (SNK-19)
PB  - Atlantis Press
SP  - 11
EP  - 13
SN  - 2590-3195
UR  - https://doi.org/10.2991/snk-19.2019.20
DO  - 10.2991/snk-19.2019.20
ID  - Cahyaningrum2019/12
ER  -