Mucolytic Activity of Flavonol Isolated from The Silver Fern (Pityrogramma calomelanos)

DOI

10.2991/snk-19.2019.21How to use a DOI?

Keywords

Pityrogramma calomelanos, flavonol, quercetine, mucolyic activity

Abstract

The aim of study is to determine the mucolytic activity of flavonol compound namely 3,5, 7,3’,4’-pentahydroxy flavone (quercetine), isolated from acetone extract of the silver fern (P. calomelanos). The mucolytic activity assay in vitro was based on the decreasing viscosity of intestinal mucus cow. The viscosity value were analyzed statistically using one way ANOVA test, followed by LSD test to determine significant differences beween treatment group. The result of mucolytic activity test showed that isolate had mucolytic activity because it showed significant differences with negative controll (phosphate buffer mucus). The isolate concentration of 0.4% had mucolytic activity which equivalent to 0.1% acetylcysteine

Copyright

© 2019, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Suyatno Sutoyo
AU  - Tukiran Tukiran
AU  - Nurul Hidajati
AU  - Nur Indah Kumalasari
PY  - 2019/12
DA  - 2019/12
TI  - Mucolytic Activity of Flavonol  Isolated from  The Silver Fern  (Pityrogramma calomelanos)
BT  - Proceedings of the National Seminar on Chemistry 2019 (SNK-19)
PB  - Atlantis Press
SP  - 8
EP  - 10
SN  - 2590-3195
UR  - https://doi.org/10.2991/snk-19.2019.21
DO  - 10.2991/snk-19.2019.21
ID  - Sutoyo2019/12
ER  -