Progress in Mechanism of E.coli K1 Crossing the Blood-brain Barrier
Xiao Yang, Huiwen Tian, Shaoyi Lin, Jie Li, Shenghe Huang, Hong Cao
Available Online January 2019.
- https://doi.org/10.2991/ssphe-18.2019.48How to use a DOI?
- E. coli K1, blood-brain barrier, Meningitis
- Meningitis is a serious central nervous system disease, E. coli K1 is the main pathogen that causes it. E.coli K1 triggers meningitis only if it crosses the blood-brain barrier(BBB), but the detail mechanism of how E. coli K1 cross the blood-brain barrier is still unclear. This article is based on current research, according to the sequence of E. coli K1 crossing the blood-brain barrier, introduce the mechanism from three sections: severe bacteremia, adhesion and invasion to brain microvascular endothelial cells (BMEC), rearrangement of cytoskeleton.
- Open Access
- This is an open access article distributed under the CC BY-NC license.
Cite this article
TY - CONF AU - Xiao Yang AU - Huiwen Tian AU - Shaoyi Lin AU - Jie Li AU - Shenghe Huang AU - Hong Cao PY - 2019/01 DA - 2019/01 TI - Progress in Mechanism of E.coli K1 Crossing the Blood-brain Barrier BT - 2nd International Conference on Social Science, Public Health and Education (SSPHE 2018) PB - Atlantis Press SP - 201 EP - 205 SN - 2352-5398 UR - https://doi.org/10.2991/ssphe-18.2019.48 DO - https://doi.org/10.2991/ssphe-18.2019.48 ID - Yang2019/01 ER -