Proceedings of the 1st Tarumanagara International Conference on Medicine and Health (TICMIH 2021)

Phytochemical Screening, Total Antioxidant Capacity, and Toxicity Test of Basil Leaf Extract (Ocimum x africanum Lour).

Authors
Timotius1, *, David Limanan2, Eny Yulianti2, F. Ferdinal2
1Faculty of Medicine, Tarumanagara University, Jakarta, Indonesia
2Staff of Department of Biochemistry and Molecular Biology, Faculty of Medicine, Tarumanagara University, Jakarta, Indonesia
*Corresponding author. Email: timotius.405180098@stu.untar.ac.id
Corresponding Author
Timotius
Available Online 1 December 2021.
DOI
https://doi.org/10.2991/ahsr.k.211130.010How to use a DOI?
Keywords
Ocimum x africanum Lour; Reactive Oxygen Species; Total Antioxidant Capacity
Abstract

High pollutant levels have caused an increase in disease that correlated with Reactive Oxygen Species through a condition that is oxidative stress. Oxidative stress can be stabilized with antioxidants by stabilizing active and unstable radicals to become inactive and stable. Basil leaves (Ocimum x africanum Lour) are known to have antioxidant capacity. The aim of this study is to determine the phytochemical profiling and antioxidant capacity of basil leaves extract. This research was conducted with an in vitro experimental study design. Extraction of this research was carried out by maceration method using methanol as solvent. The tests were carried out in the form of phytochemical tests to determine the content of secondary metabolites and antioxidant capacity tests using the DPPH method. In phytochemical test of basil leaf extract, it was found positive for secondary metabolites of alkaloids, anthocyanins, cardio glycosides, coumarins, Flavonoid, glycosides, phenols, quinones, saponins, steroid, terpenoids and tannins and the antioxidant capacity test obtained IC50 of 174.04 μg/mL. In this study we found that basil leaves contain secondary metabolites and antioxidants capacity but not as much as vitamin C, even though basil leave antioxidant capacity not as much as vitamin C, basil leave have other compound like Linalool that have antimicrobial and antioxidant activity, beside vitamin C also can induce acid reflux, so it can be concluded that basil leaves have secondary metabolites and the antioxidant capacity.

Copyright
© 2021 The Authors. Published by Atlantis Press International B.V.
Open Access
This is an open access article under the CC BY-NC license.

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Volume Title
Proceedings of the 1st Tarumanagara International Conference on Medicine and Health (TICMIH 2021)
Series
Advances in Health Sciences Research
Publication Date
1 December 2021
ISBN
978-94-6239-473-5
ISSN
2468-5739
DOI
https://doi.org/10.2991/ahsr.k.211130.010How to use a DOI?
Copyright
© 2021 The Authors. Published by Atlantis Press International B.V.
Open Access
This is an open access article under the CC BY-NC license.

Cite this article

TY  - CONF
AU  - Timotius
AU  - David Limanan
AU  - Eny Yulianti
AU  - F. Ferdinal
PY  - 2021
DA  - 2021/12/01
TI  - Phytochemical Screening, Total Antioxidant Capacity, and Toxicity Test of Basil Leaf Extract (Ocimum x africanum Lour).
BT  - Proceedings of the 1st Tarumanagara International Conference on Medicine and Health (TICMIH 2021)
PB  - Atlantis Press
SP  - 52
EP  - 56
SN  - 2468-5739
UR  - https://doi.org/10.2991/ahsr.k.211130.010
DO  - https://doi.org/10.2991/ahsr.k.211130.010
ID  - 2021
ER  -