Proceedings of the 1st Tarumanagara International Conference on Medicine and Health (TICMIH 2021)

Phytochemical Screening, Total Antioxidant Capacity and Toxicity Test of White Jasmine Flower Extract (Jasminum sambac)

Authors
Vincent Suaputra1, *, David Limanan2, Eny Yulianti2, Frans Ferdinal2
1Faculty of Medicine, Tarumanagara University, Jakarta, Indonesia
2Staff of Departement of Biochemistry and Molecular Biology, Faculty of Medicine, TarumanagaraUniversity, Jakarta, Indonesia
*Corresponding author: Email: vincent.suaputra@gmail.com
Corresponding Author
Vincent Suaputra
Available Online 1 December 2021.
DOI
https://doi.org/10.2991/ahsr.k.211130.009How to use a DOI?
Keywords
Jasminum sambac; Phytochemical Screening; DPPH; Brine Shrimp Lethality Test
Abstract

Oxidative stress is a state of imbalance of antioxidants and reactive oxygen species levels in the body. Prolonged oxidative stress can cause degenerative diseases, malignancies, or premature aging. This situation can be prevented by antioxidants, compounds that can inhibit the oxidation process. One of the Indonesian plants, namely white jasmine flower, is known to contain a lot of secondary metabolites and have the potential to be antioxidants. Therefore, this research was conducted to determine the content of secondary metabolites, antioxidant potential, and toxicity of white jasmine flowers. Jasmine flower extract was made by maceration method using methanol solvent. Phytochemical screening was carried out in a semi-qualitative manner based on Harborne’s book. The total antioxidant capacity test was carried out by the Blois method using DPPH (1,1-diphenyl-2-picrylhydrazyl) solution. Toxicity test was carried out using the BSLT (Brine Shrimp Lethality Test) method. In the phytochemical screening, jasmine flower extract was found alkaloids, flavonoids, cardio glycosides, glycosides, saponins, coumarins, phenolics, quinones, betacyanins, steroids, terpenoids, and tannins. It was found that jasmine flower extract had a total antioxidant capacity (IC50 = 460.24 µg/mL) which was categorized as weak antioxidant (200 ppm ≤ IC50 ≤ 500 ppm), and the level of toxicity (LC50 = 111.43 µg/mL) which has cytotoxic properties (LC50 ≤ 1000 ppm) and belongs to the moderate toxic category (100 ppm ≤ LC50 ≤ 1000 ppm). In summary, jasmine flower extract has the potential as an antioxidant and has the potential to be an antimitotic agent.

Copyright
© 2021 The Authors. Published by Atlantis Press International B.V.
Open Access
This is an open access article under the CC BY-NC license.

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Volume Title
Proceedings of the 1st Tarumanagara International Conference on Medicine and Health (TICMIH 2021)
Series
Advances in Health Sciences Research
Publication Date
1 December 2021
ISBN
978-94-6239-473-5
ISSN
2468-5739
DOI
https://doi.org/10.2991/ahsr.k.211130.009How to use a DOI?
Copyright
© 2021 The Authors. Published by Atlantis Press International B.V.
Open Access
This is an open access article under the CC BY-NC license.

Cite this article

TY  - CONF
AU  - Vincent Suaputra
AU  - David Limanan
AU  - Eny Yulianti
AU  - Frans Ferdinal
PY  - 2021
DA  - 2021/12/01
TI  - Phytochemical Screening, Total Antioxidant Capacity and Toxicity Test of White Jasmine Flower Extract (Jasminum sambac)
BT  - Proceedings of the 1st Tarumanagara International Conference on Medicine and Health (TICMIH 2021)
PB  - Atlantis Press
SP  - 45
EP  - 51
SN  - 2468-5739
UR  - https://doi.org/10.2991/ahsr.k.211130.009
DO  - https://doi.org/10.2991/ahsr.k.211130.009
ID  - Suaputra2021
ER  -