Gender differences in bicycle exercise stress echocardiography testing

Karsten Keller; Kathrin Stelzer; Martin Geyer; Thomas Münzel; Mir Abolfazl Ostad

doi:10.1016/j.artres.2018.02.002

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Volume 22, Issue C, June 2018, Pages 8 - 16

Gender differences in bicycle exercise stress echocardiography testing

Authors

Karsten Keller^a^{, b}^{, *}, Kathrin Stelzer^b, Martin Geyer^b, Thomas Münzel^b^{, a}^{, c}, Mir Abolfazl Ostad^b

^aCenter for Thrombosis and Hemostasis, University Medical Center Mainz, Johannes Gutenberg-University Mainz, Germany

^bCenter of Cardiology, Cardiology I, University Medical Center Mainz, Johannes Gutenberg-University Mainz, Germany

^cGerman Center for Cardiovascular Research, Partner Site Rhine Main, Mainz, Germany

^*Corresponding author. Center for Thrombosis and Hemostasis, University Medical Center Mainz (Johannes Gutenberg-University Mainz), Langenbeckstr. 1, 55131 Mainz Germany. Fax: +0049 6131 17 8461. E-mail address: Karsten.Keller@unimedizin-mainz.de (K. Keller).

Corresponding Author

Karsten Keller

Received 9 November 2017, Revised 21 December 2017, Accepted 5 February 2018, Available Online 21 February 2018.

DOI: 10.1016/j.artres.2018.02.002 How to use a DOI?
Keywords: Exercise testing; Stress echocardiography; Sex; Gender
Abstract: Background: Sex-specific differences for myocardial infarction and coronary artery disease (CAD) have been reported in several studies. The aim of our present study was to identify gender-specific differences regarding bicycle-exercise-stress-echocardiography.

Methods: We compared 87 (69.0%) male and 39 (31.0%) female patients with suspected or known stable coronary artery disease (CAD), who underwent bicycle-exercise stress-echocardiography.

Results: False-positive exercise-test results were more prevalent in females (21.1% vs. 17.4%) and arterial hypertension was connected with false-positive results in women only. In males, higher peak-exercise heart-rate was accompanied by lower risk of false-positive stress-echocardiography results. Higher systolic peak blood pressure during exercise was related to a higher risk for pending coronary artery interventions in females, whereas higher peak heart-rate during exercise was accompanied by a lower risk for pending coronary artery interventions also in females.

Conclusions: Exercise-echocardiography demonstrated significant sex-specific differences. Higher efforts during stress-test lead to better test-accuracy.
Open Access: This is an open access article distributed under the CC BY-NC license.

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Journal: Artery Research
Volume-Issue: 22 - C
Pages: 8 - 16
Publication Date: 2018/02/21
ISSN (Online): 1876-4401
ISSN (Print): 1872-9312
DOI: 10.1016/j.artres.2018.02.002 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

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ris enw bib

TY  - JOUR
AU  - Karsten Keller
AU  - Kathrin Stelzer
AU  - Martin Geyer
AU  - Thomas Münzel
AU  - Mir Abolfazl Ostad
PY  - 2018
DA  - 2018/02/21
TI  - Gender differences in bicycle exercise stress echocardiography testing
JO  - Artery Research
SP  - 8
EP  - 16
VL  - 22
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2018.02.002
DO  - 10.1016/j.artres.2018.02.002
ID  - Keller2018
ER  -

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