Analysis of Vascular Aging in Arterial Hypertension – Population-based Study: Preliminary Results

DOI

10.2991/artres.k.191201.001How to use a DOI?

Keywords

Aging; arterial hypertension; population study

Abstract

Background: Arterial Hypertension (AH) is an uncertain and complex physiopathological disease with the Arterial Stiffness (AS) as one of the main cardiovascular alterations. Pulse Wave Velocity (PWV) is the gold standard marker for assessment of the vascular aging and an important predictor of cardiovascular risk.

Methods: Cross-sectional population-based studies, in the restricted area of Vale do Ogunjá, Salvador-Bahia. Sociodemographic data, through questionnaire and clinical data were obtained. A PWV was evaluated by applanation tonometry using the device SphygmoCor^® (AtCor Medical Pty Ltd, New South Wales, Australia). Frequency and descriptive measurements of central and dispersion were obtained, and the Chi-square test to statistical analysis.

Results: PWV presented a higher mean in hypertensive patients (10.0 ± 2.2 m/s). There was a higher prevalence of AS in male individuals with advanced age and presence of risk factors. The prevalence ratio of AS was 3.7 times higher in hypertensive patients (p = 0.002; 95% CI: 1.6–8.5) and 7.5 times higher in patients aged above 40–74 years (p = 0.015; 95% CI: 2.4–23.1).

Conclusion: There was an important relation between AS and increased of PWV in the presence of hypertension. The relevance of this study is associated with the use of non-invasive clinical evaluation of PWV, contributing to improve morbidity and mortality in hypertensive patients.

HIGHLIGHTS

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  Important association between arterial stiffness and arterial hypertension.

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  Prevalence of arterial stiffness in the male gender, advanced age.

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  Prevalence of arterial stiffness with high BMI, dyslipidemia and dysglycemia DM.

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  Arterial stiffness associated to age, schooling level, BMI and arterial hypertension.

Copyright

© 2019 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.

Open Access

This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - JOUR
AU  - Juan Jailson Oliveira Almeida Costa
AU  - Roberta de Castro Araújo Cunha
AU  - Antonio de Assis Oliveira Alves Filho
AU  - Larissa Ribeiro Bessa
AU  - Rodrigo Lins Sant’Ana de Lima
AU  - Alana dos Reis Silva
AU  - Brenno Araújo e Souza
AU  - Catarina de Almeida Viterbo
AU  - Mariana Barreto Requião
AU  - Daniele Brustolim
AU  - Diorlene Oliveira da Silva
AU  - Lucélia Batista Neves Cunha Magalhães
AU  - Cecília Freitas da Silva Araújo
PY  - 2019
DA  - 2019/12/13
TI  - Analysis of Vascular Aging in Arterial Hypertension – Population-based Study: Preliminary Results
JO  - Artery Research
SP  - 131
EP  - 138
VL  - 25
IS  - 3-4
SN  - 1876-4401
UR  - https://doi.org/10.2991/artres.k.191201.001
DO  - 10.2991/artres.k.191201.001
ID  - Costa2019
ER  -