Artery Research

Volume 25, Issue 3-4, December 2019
Mini Review

1. Hypertension: Protective Effects of Physical Exercise on Cognition Function, Arterial Function and Brain Health

Marinei Lopes Pedralli, Eduardo Barbosa, Pedro Guimarães Cunha
Pages: 81 - 86
Systemic Arterial Hypertension (SAH) is a chronic condition that requires clinical treatment and is associated with increased risk of cognitive impairment and dementia. Therefore, strategies with fewer side effects and less invasive procedures are required. Evidence supports that Physical Exercise (PE)...
Research Article

2. Decoupling of Heart Rate and Blood Pressure: Hemodynamic Counter-regulatory Mechanisms and their Implications

Joseph Lewis Izzo, Muhammed Absar Anwar, Kalamaini Elango, Rahil Ahmed, Peter Osmond
Pages: 87 - 94
To investigate the dynamic relationships among Heart Rate (HR) and systemic hemodynamics in everyday life, we performed 24-h ambulatory pulse wave analyses (Mobil-O-Graph) in individuals with normal and elevated BP (n = 116) and in a double-blinded cross-over study where HR was varied pharmacologically...
Research Article

3. Association between Aortic Stiffness and Cerebral Pulsatility is Modestly Influenced by Augmentation Index

James Pearson, Laura J. Watkeys, James M. Coulson, Zachary J. Schlader, Craig G. Crandall, John R. Cockcroft, Carmel M. McEniery, Barry J. McDonnell
Pages: 95 - 100
Central Pulse Pressure (CPP) and Aortic Pulse Wave Velocity (aPWV) share a positive relationship with cerebral pulsatility and are associated with cerebrovascular disorders including stroke. Our aim was to examine the influence of Augmentation Index (AIx) upon this relationship, first by using a cross...
Research Article

4. Central Hemodynamic Parameters are Altered in Resistant Hypertensive Individuals

João Marcos de Menezes Zanatta, Fábio dos Santos Ricardi, Elizabeth do Espírito Santo Cestário, Tatiana Azevedo, Jéssica Rodrigues Uyemura, Luciana Neves Cosenso-Martin, Juan Carlos Yugar-Toledo, José Fernando Vilela-Martin
Pages: 101 - 105
Background: Systemic arterial hypertension (SAH) is one of the major risk factors related to the development of cardiovascular diseases (CVD). Sodium intake is linked to elevated blood pressure and can be estimated by 24-h urinary sodium excretion. The objective of this study was to correlate 24 h urinary...
Research Article

5. Altered Central Hemodynamics in Individuals with Down Syndrome

Thessa Irena Maria Hilgenkamp, Elizabeth Cornellia Schroeder, Sang Ouk Wee, Georgios Grigoriadis, Alexander Jacob Rosenberg, Tracy Baynard, Bo Fernhall
Pages: 107 - 112
Background: Individuals with Down Syndrome (DS) have autonomic dysfunction impacting regulation of heart rate, Blood Pressure (BP), and peripheral vasoconstriction. This may alter central hemodynamics through different wave reflections. We investigated central hemodynamics including wave reflection during...
Research Article

6. Serum 25-Hydroxyvitamin D Deficiency and Insufficiency are Associated with Ankle-Brachial Index but not Arterial Stiffness in an Elderly Community-dwelling Chinese Population

Junli Zuo, Kun Qian, Yan He, Isabella Tan, Mark Butlin, Alberto Avolio, Peizhan Chen
Pages: 113 - 119
Vitamin D deficiency may increase arterial stiffness, a sub-clinical symptom of Target Organ Damage (TOD). This study aimed to investigate the associations between total serum vitamin D level and arterial stiffness assessed by brachial-ankle Pulse Wave Velocity (baPWV) and atherosclerosis assessed by...
Research Article

7. Assessment of Arterial Stiffness by Brachial Oscillometry in Community Pharmacies for Managing Hypertension (COPHARTEN)☆

Enrique Rodilla, Rosa Prats, Otón Bellver, Javier Reig, Pedro Cunha, María Teresa Climent
Pages: 121 - 130
Background and Objective: Arterial Stiffness (AS) measured as pulse wave velocity has emerged in recent years as a hypertension mediated organ damage with independent prognostic value for Cardiovascular (CV) diseases that has also been discussed as a potential cause of Hypertension (HTN). The aim of...
Research Article

8. Analysis of Vascular Aging in Arterial Hypertension – Population-based Study: Preliminary Results

Juan Jailson Oliveira Almeida Costa, Roberta de Castro Araújo Cunha, Antonio de Assis Oliveira Alves Filho, Larissa Ribeiro Bessa, Rodrigo Lins Sant’Ana de Lima, Alana dos Reis Silva, Brenno Araújo e Souza, Catarina de Almeida Viterbo, Mariana Barreto Requião, Daniele Brustolim, Diorlene Oliveira da Silva, Lucélia Batista Neves Cunha Magalhães, Cecília Freitas da Silva Araújo
Pages: 131 - 138
Background: Arterial Hypertension (AH) is an uncertain and complex physiopathological disease with the Arterial Stiffness (AS) as one of the main cardiovascular alterations. Pulse Wave Velocity (PWV) is the gold standard marker for assessment of the vascular aging and an important predictor of cardiovascular...
Research Article

9. Influence of Ultrasound Settings on Carotid Biomarker Assessment by B-mode Image Processing

Martina Francesconi, Vincenzo Gemignani, Rachele Gherardini, Nicole Di Lascio, Francesco Faita, Lorenzo Ghiadoni, Rosa Maria Bruno, Elisabetta Bianchini
Pages: 139 - 144
Introduction: This study aims to investigate how image settings affect carotid Intima-Media-Thickness (IMT) and diameter estimation performed with Carotid Studio (Quipu-Srl). Methods: Fourteen healthy volunteers (24.4 ± 4.4 years; eight men) were recruited. Longitudinal scans 3-cm-deep of common-carotid-arteries...
Research Article

10. Home Blood Pressure Assessment in Children with Autism Spectrum Disorder: A Feasibility Study

Kevin S. Heffernan, Luis Columna, Laura Prieto, Patricia Pagan, Jacob DeBlois, Alyssa Prawl, Gianpietro Revolledo, Natalie Russo, Tiago V. Barreira
Pages: 145 - 149
Introduction: Measurement of Blood Pressure (BP) in children provides insight into future Cardiovascular Disease (CVD) risk. Objective: To examine the feasibility and reliability of home BP monitoring in children with Autism Spectrum Disorder (ASD) and compare to office BP measurement. Methods: Seven...
Research Article

11. Physical Fitness is a Mediator in the Relationship between Arterial Stiffness and Cognitive Function

Alinne Nascimento, Duarte Barros, José Oliveira, Joana Carvalho, Lucimere Bohn
Pages: 151 - 155
Background: To investigate physical fitness as a mediator of the relationship between arterial stiffness and cognitive function in seniors. Methods: This is a cross-sectional study comprising 155 individuals free from chronic diseases (75.5 ± 6.5 years; 69.7% female). Carotid-femoral pulse wave was...
Research Article

12. Nigella sativa Extract and Thymoquinone Regulate Inflammatory Cytokine and TET-2 Expression in Endothelial Cells

Jason Amartey, Samuel Gapper, Nurudeen Hussein, Keith Morris, Cathryn E. Withycombe
Pages: 157 - 163
Numerous natural compounds including Nigella sativa (N. sativa) demonstrate anti-inflammatory and anti-diabetic antiangiogenic properties. Lipopolysaccharide (LPS) mediated inflammation is regarded as an important contributor to the inflammation that is associated with the development of arteriosclerosis....
Research Article

13. Dissociation of Carotid and Forearm Pressure Decay Constants (tau), Windkessel Compliances, and Pulse Wave Velocities: Implications for Circulatory Models

Joseph Lewis Izzo, Muhammed Absar Anwar, Sherif Elsayed, Peter John Osmond, Benjamin Gavish
Pages: 165 - 169
Windkessel (WK) models have often been used to simulate the arterial circulation. We studied a critical characteristic of WK function, the arterial pressure-decay constant tau, to test whether all arterial regions share the same WK characteristics, which should theoretically be related to arterial stiffness....