Artery Research

Volume 6, Issue 3, September 2012, Pages 109 - 113

Non-invasive estimates of central systolic blood pressure: Comparison of the Centron cBP301 and SphygmoCor devices

Authors
Ann-Marie Mekhaila, Lisa M. Dayb, Anna K. Goodhartb, Ian B. Wilkinsonb, Carmel M. McEnieryb, *
aWellington School of Medicine, Wellington Hospital, Otago University, New Zealand
bClinical Pharmacology Unit, University of Cambridge, Addenbrooke’s Hospital, Box 110, Cambridge CB2 0QQ, United Kingdom
*Corresponding author. Tel.: +44 1223336806. E-mail address: cmm41@cam.ac.uk (C.M. McEniery).
Corresponding Author
Carmel M. McEniery
Received 29 May 2012, Revised 6 July 2012, Accepted 9 July 2012, Available Online 24 July 2012.
DOI
10.1016/j.artres.2012.07.001How to use a DOI?
Keywords
Blood pressure; Aortic pressure; Centron; SphygmoCor; Transfer function; Pulse wave analysis
Abstract

Background: Central systolic blood pressure (cSBP) may be more predictive of cardiovascular events than brachial BP. Therefore, non-invasive methods of determining central BP, which are suitable for routine clinical use, are required. The aim of this study was to compare estimates of cSBP provided by the Centron cBP301 with those obtained with the widely used SphygmoCor system.

Methods: In 60 subjects (30 females), age range 22–90 years, brachial BP was measured using the Centron device and then cSBP estimated using the Centron, and then SphygmoCor. In a subset of 16 subjects (8 females), measurements were repeated at rest and following the administration of glyceryl trinitrate (GTN).

Results: There was a strong correlation (r = 0.98; P < 0.001) between the estimates of cSBP obtained with each device. There was also good agreement between devices, with a mean difference (±SD) of 0.2 ± 3.5 mmHg (P = 0.5). Similarly, the devices were highly correlated and in good agreement following the administration of GTN, with the mean difference in cSBP ranging from 0.5 ± 3.9 mmHg to 2.3 ± 3.7 mmHg, across the measurement period.

Conclusion: The Centron cBP301 and SphygmoCor devices produce similar estimates of cSBP, both at rest and in response to a pharmacological challenge. The Centron device is potentially suitable for routine clinical monitoring of central BP.

Copyright
© 2012 Association for Research into Arterial Structure and Physiology. Published by Elsevier B.V. All rights reserved.
Open Access
This is an open access article distributed under the CC BY-NC license.

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Journal
Artery Research
Volume-Issue
6 - 3
Pages
109 - 113
Publication Date
2012/07/24
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2012.07.001How to use a DOI?
Copyright
© 2012 Association for Research into Arterial Structure and Physiology. Published by Elsevier B.V. All rights reserved.
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - JOUR
AU  - Ann-Marie Mekhail
AU  - Lisa M. Day
AU  - Anna K. Goodhart
AU  - Ian B. Wilkinson
AU  - Carmel M. McEniery
PY  - 2012
DA  - 2012/07/24
TI  - Non-invasive estimates of central systolic blood pressure: Comparison of the Centron cBP301 and SphygmoCor devices
JO  - Artery Research
SP  - 109
EP  - 113
VL  - 6
IS  - 3
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2012.07.001
DO  - 10.1016/j.artres.2012.07.001
ID  - Mekhail2012
ER  -