Artery Research

<Previous Article In Issue
Next Article In Issue>
Volume 24, Issue C, December 2018, Pages 82 - 82

P8 THE EFFECT OF CAFFEINE ON MENTAL STRESS RELATED CARDIOVASCULAR RESPONSE

Authors
Ziva Melik1, Ksenija Cankar2
1Unversity of Ljubljana, Faculty of medicine, Institute of physiology, Ljubljana, Slovenia
2University of Ljubljana, Faculty of Medicine, Institute of Physiology, Ljubljana, Slovenia
Available Online 4 December 2018.
DOI
10.1016/j.artres.2018.10.061How to use a DOI?
Abstract

Background: Caffeine, the most widely used pharmacologically active substance causes mental stimulation and a slight raising of blood pressure. The aim of our work was to evaluate the effect of caffeine on the cardiovascular system during rest and during mental stress.

Methods: RR interval duration, arterial blood pressure and Laser-Doppler (LD) flux were monitored in 40 healthy volunteers (aged 21.98 ± 0.9 years) before and after ingestion of 200 mg of caffeine. The measurements were performed during rest (360s), during mental stress (90s) and during relaxation after mental stress (510s). The measurements were performed twice: under the effect of caffeine and under the effect of placebo. The study was approved by the National Medical Ethics Committee; written informed consent was obtained from each subject.

Results: During resting condition RR interval (ms) increased (910,49 ± 130,5 before and 958,96 ± 130,66 after) (p<0,05), systolic blood pressure (mm Hg) increased (119,35 ± 14,3 before and 127,54 ± 15,9 after) (p<0,05), diastolic blood pressure (mm Hg) increased (68,78 ± 11,2 and 76,20 ± 11,6) (p<0,05), LD flux decreased (150,05 ± 96,4 and 115,15 ± 86,7) (p<0,05) and temperature decreased (30,92 ± 3,5 and 29,71 ± 3,5) (p<0,05) after ingestion of caffeine. During mental stress systolic and diastolic blood pressure increased significantly less, RR interval was nearly the same and LD flux after mental stress increased more and earlier after ingestion of caffeine.

Conclusion: Although caffeine raises blood pressure it has favourable effect on the cardiovascular system during and after mental stress.

Open Access
This is an open access article distributed under the CC BY-NC license.

Download article (PDF)
View full text (HTML)

<Previous Article In Issue
Next Article In Issue>
Journal
Artery Research
Volume-Issue
24 - C
Pages
82 - 82
Publication Date
2018/12/04
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2018.10.061How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - Ziva Melik
AU  - Ksenija Cankar
PY  - 2018
DA  - 2018/12/04
TI  - P8 THE EFFECT OF CAFFEINE ON MENTAL STRESS RELATED CARDIOVASCULAR RESPONSE
JO  - Artery Research
SP  - 82
EP  - 82
VL  - 24
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2018.10.061
DO  - 10.1016/j.artres.2018.10.061
ID  - Melik2018
ER  -