Artery Research

Volume 24, Issue C, December 2018, Pages 114 - 114

P121 ASSOCIATION OF CARDIORESPIRATORY FITNESS WITH ARTERIAL STIFFNESS AND PERIPHERAL AND CENTRAL BLOOD PRESSURE IN RESISTANT HYPERTENSION PATIENTS

Authors
Catarina Garcia1, Susana Lopes1, Susana Bertoquini2, Verónica Ribau3, Cátia Leitão4, Daniela Figueiredo5, Ilda P Ribeiro6, Joana Barbosa de Melo6, João L Viana7, José Mesquita-Bastos5, Jorge Polónia2, Fernando Ribeiro1, Alberto J Alves8
1School of Health Sciences and Institute of Biomedicine - iBiMED, University of Aveiro, Aveiro, Portugal
2Faculty of Medicine, University of Porto, & Hypertension Unit, ULS, Matosinhos, Portugal
3Department, Hospital Infante D. Pedro, Centro Hospitalar do Baixo Vouga, Aveiro, Portugal
4Departmente of Physics & I3N and Instituto de Telecomunicações, University of Aveiro, Portugal
5School of Health Sciences and CINTESIS@UA, University of Aveiro, Portugal
6Center of Investigation on Environment Genetics and Oncobiology (CIMAGO), Faculty of Medicine, University of Coimbra, and Center for Neuroscience and Cell Biology and Institute for Biomedical Imaging and Life Sciences (CNC.IBILI), Coimbra, Portugal
7Sports Sciences, Health Sciences and Human Development – CIDESD, University Institute of Maia, Portugal
8Sports Sciences, Health Sciences and Human Development – CIDESD, University Institute of Maia, Portugal
Available Online 4 December 2018.
DOI
10.1016/j.artres.2018.10.174How to use a DOI?
Abstract

Background: The relationship between arterial stiffness, blood pressure (BP) and cardiorespiratory fitness (CRF) has been studied in healthy populations and cardiovascular patients, since all of which proved to be independent predictors of all-cause mortality. We aimed to investigate the association of CRF with arterial stiffness and peripheral and central hemodynamics, in patients with resistant hypertension (RT).

Methods: In this cross-sectional study, 30 patients (13 men, 17 women; age, 57.7 ± 8.1 years; weight, 79.2 ± 11.6 kg; body mass index, 29.7 ± 4.0 kg/m2) with resistant hypertension were recruited in the Hospital Infante D. Pedro (Aveiro) and Hospital Pedro Hispano (Matosinhos). Outcome measures included CRF (VO2peak), peripheral and central BP, and carotid-femoral pulse wave velocity (cf-PWV). Correlation analysis was conducted to assess the association between variables.

Results: A significant negative correlation was found between VO2peak (33.7 ± 6.2 mLO2/kg/min) and central (141.0±21.3 mmHg; r = −0.395, p = 0.031) and peripheral systolic BP (148.4 ± 21.3 mmHg; r = −0.363, p = 0.049). VO2peak was also correlated with pulse pressure (PP) amplification ratio (1.2 ± 0.1 mmHg; r = 0.361, p = 0.050). The association with central systolic BP (r = −0.403, p = 0.035) and PP amplification ratio (r = 0.408, p = 0.033) remained significant after adjusted for age. VO2peak showed no correlation with PWV (9.4 ± 2.9 m/s; r = −0.075, p = 0.694) and peripheral (88.1 ± 12.2 mmHg; r = −0.138 p = 0.467) and central diastolic BP (88.5 ± 12.7 mmHg; r = −0.133, p = 0.483).

Conclusion: This study confirms the inverse relationship between CRF and central systolic BP and PP amplification ratio in RH patients, regardless of age.

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Journal
Artery Research
Volume-Issue
24 - C
Pages
114 - 114
Publication Date
2018/12/04
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2018.10.174How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - JOUR
AU  - Catarina Garcia
AU  - Susana Lopes
AU  - Susana Bertoquini
AU  - Verónica Ribau
AU  - Cátia Leitão
AU  - Daniela Figueiredo
AU  - Ilda P Ribeiro
AU  - Joana Barbosa de Melo
AU  - João L Viana
AU  - José Mesquita-Bastos
AU  - Jorge Polónia
AU  - Fernando Ribeiro
AU  - Alberto J Alves
PY  - 2018
DA  - 2018/12/04
TI  - P121 ASSOCIATION OF CARDIORESPIRATORY FITNESS WITH ARTERIAL STIFFNESS AND PERIPHERAL AND CENTRAL BLOOD PRESSURE IN RESISTANT HYPERTENSION PATIENTS
JO  - Artery Research
SP  - 114
EP  - 114
VL  - 24
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2018.10.174
DO  - 10.1016/j.artres.2018.10.174
ID  - Garcia2018
ER  -