Artery Research

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Volume 24, Issue C, December 2018, Pages 125 - 126

P157 AORTIC CALCIFICATIONS AND INFLAMMATION ARE ASSOCIATED WITH IN-HOSPITAL COMPLICATIONS IN ACUTE CORONARY SYNDROME

Authors
Konstantia-Paraskevi Gkini, Dimitrios Terentes-Printzios, Charalambos Vlachopoulos, Iosif Koutagiar, Angeliki Rigatou, Stavroula Pantou, Christos Georgakopoulos, Dimitrios Tousoulis
Hypertension and Cardiometabolic Syndrome Unit, 1st Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Hippokration Hospital, Athens, Greece
Available Online 4 December 2018.
DOI
10.1016/j.artres.2018.10.210How to use a DOI?
Abstract

Purpose/Background/Objectives: Aortic calcifications and inflammation are independent predictors of adverse cardiovascular events. We sought to investigate the association of aortic calcifications and inflammation with in-hospital morbidity and mortality of patients with acute coronary syndrome (ACS).

Methods: Two hundred patients (mean age 66 ± 15 years, 150 males) admitted to our Hospital with ACS from 2016-2017 were included in the study. The extent of aortic arch calcification (AAC) on a postero-anterior plain chest X-ray was divided into four grades (0 to 3). Grades 0 to 1 and grades 2 to 3 were categorized as lower and higher AAC grade respectively. High-sensitivity C-reactive protein (hsCRP) was also assessed. In-hospital complications that included reinfarction, arrhythmias, heart failure, stroke, mechanical complications, renal failure, surgery and death were assessed in all patients.

Results: The majority of patients (n = 132, 66%) presented with non-ST elevation ACS, whereas 68 patients as ST-elevation myocardial infarction (STEMI) (n = 68, 34%). Seventy-seven (38.5%) patients presented with one or more in-hospital complications (6 of them died). Higher AAC grade was visible in 44 patients (22%). Patients with higher AAC had increased risk (Odds ratio [OR] = 2.29, 95% Confidence intervals [CI] 1.03 to 5.12, p = 0.043) for in hospital complications after adjusting for age, gender, STEMI/NSTE-ACS diagnosis (OR = 4.10, 95% CI 2.08 to 8.05 for STEMI diagnosis, p < 0.001) and hsCRP (OR = 1.80, 95% CI 1.10 to 2.93, p = 0.02).

Conclusions: Our study shows that simple tools can be used to assess the in-hospital risk of ACS patients. It also highlights the prognostic role of arterial stiffness and low-grade inflammation in ACS.

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<Previous Article In Issue
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Journal
Artery Research
Volume-Issue
24 - C
Pages
125 - 126
Publication Date
2018/12/04
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2018.10.210How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - Konstantia-Paraskevi Gkini
AU  - Dimitrios Terentes-Printzios
AU  - Charalambos Vlachopoulos
AU  - Iosif Koutagiar
AU  - Angeliki Rigatou
AU  - Stavroula Pantou
AU  - Christos Georgakopoulos
AU  - Dimitrios Tousoulis
PY  - 2018
DA  - 2018/12/04
TI  - P157 AORTIC CALCIFICATIONS AND INFLAMMATION ARE ASSOCIATED WITH IN-HOSPITAL COMPLICATIONS IN ACUTE CORONARY SYNDROME
JO  - Artery Research
SP  - 125
EP  - 126
VL  - 24
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2018.10.210
DO  - 10.1016/j.artres.2018.10.210
ID  - Gkini2018
ER  -