Artery Research

Volume 24, Issue C, December 2018, Pages 125 - 125

P155 DETERMINANTS OF PULSE WAVE VELOCITY IN CHILDREN

Authors
Cristina Silva1, Mariana Formigo1, Nuno Formigo2, 3, Sara Freitas1, Cristina Cunha1, Margarida Rocha1, Clarisse Neves1, Laura Castro1, Filipe Gonçalves1, Maria J. Cotter4, Pedro G. Cunha1, 5, 6, Jorge Cotter1, 5, 6
1Center for the Research and Treatment of Arterial Hypertension and Cardiovascular Risk, Hospital Senhora da Oliveira, Guimarães, Portugal
2Department of Biology, Faculty of Sciences of University of Porto, Portugal
3CIIMAR - Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Portugal
4Department of Natural Sciences, Escola E.B. 2,3 João de Meira, Guimarães, Portugal
5Life and Health Sciences Research Institute, School of Medicine, University of Minho, Braga, Portugal
6ICVS/3B’s - PT Government Associate Laboratory, Braga/Guimarães, Portugal
Available Online 4 December 2018.
DOI
10.1016/j.artres.2018.10.208How to use a DOI?
Abstract

Background: Arterial stiffening measured by Pulse Wave Velocity (PWV) predicts cardiovascular events and mortality in adults. It advances with age and seems accelerated in children with certain disease conditions such as chronic kidney disease or diabetes. The aim of this study was to determine factors that influence PWV in children.

Methods: PWV was captured in 285 children aged 10–14 years attending a Portuguese school. The effects of sex, age, height, weight, body mass index, waist circumference, blood pressure, heart rate and sodium excretion in 24-h urinary samples in PWV were tested.

Results: PWV correlated positively with age, height, systolic blood pressure, diastolic blood pressure and heart rate in males and females (p < 0.05) and with weight in males (p < 0.05). Major predictors for PWV in a multivariate regression analysis were gender, height, weight, diastolic blood pressure, heart rate and body mass index.

Conclusion: Our study found several determinants of PWV in children, some of them modifiable and interfering with cardiovascular outcomes. Future research may provide clarity to the association between PWV in children and cardiovascular events in adulthood.

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Journal
Artery Research
Volume-Issue
24 - C
Pages
125 - 125
Publication Date
2018/12/04
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2018.10.208How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - JOUR
AU  - Cristina Silva
AU  - Mariana Formigo
AU  - Nuno Formigo
AU  - Sara Freitas
AU  - Cristina Cunha
AU  - Margarida Rocha
AU  - Clarisse Neves
AU  - Laura Castro
AU  - Filipe Gonçalves
AU  - Maria J. Cotter
AU  - Pedro G. Cunha
AU  - Jorge Cotter
PY  - 2018
DA  - 2018/12/04
TI  - P155 DETERMINANTS OF PULSE WAVE VELOCITY IN CHILDREN
JO  - Artery Research
SP  - 125
EP  - 125
VL  - 24
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2018.10.208
DO  - 10.1016/j.artres.2018.10.208
ID  - Silva2018
ER  -