Artery Research

Volume 25, Issue Supplement 1, December 2019, Pages S101 - S101

P60 Invasive Validation of Antares, a New Algorithm to Calculate Central Blood Pressure from Oscillometric Upper Arm Pulse Waves

Authors
Marcus Doerr1, 2, Stefan Richter3, Siegfried Eckert4, Marc-Alexander Ohlow3, Fabian Hammer1, Astrid Hummel1, Vivien Dornberger1, Elisabeth Genzel1, Johannes Baulmann5, 6, *
1Department of Internal Medicine B, University Medicine Greifswald, Germany
2German Centre for Cardiovascular Research (DZHK), partner site Greifswald, Germany
3Zentralklinik Bad Berka GmbH, Herzzentrum, Department of Cardiology, Germany
4Klinik für Allgemeine und Interventionelle Kardiologie/Angiologie, Universitätsklinik der Ruhr-Universität Bochum, Bad Oeynhausen, Germany
5Medizinische Universität Graz, Austria
6European Prevention Center, Düsseldorf, Germany
*Corresponding author. Email: jbaulmann@yahoo.com
Corresponding Author
Johannes Baulmann
Available Online 17 February 2020.
DOI
10.2991/artres.k.191224.091How to use a DOI?
Abstract

Background: Antares is an algorithm for pulse wave analysis (PWA) by oscillometric blood pressure monitors in order to estimate central (aortic) blood pressure (cBP). Antares aims to enable brachial cuff-based blood pressure (BP) monitors to be type II-devices, determining absolute cBP values independently of potential peripheral BP inaccuracies. The present study is an invasive validation of the Antares algorithm.

Methods: We followed entirely the 2017 ARTERY protocol for validation of non-invasive cBP devices, the 2013 ANSI/AAMI/ISO 81060-2 and 2018 AAMI/ESH/ISO validation standard protocols. In total, 191 patients undergoing cardiac catheterization were included, of which 145 patients entered analysis. Invasive cBP recordings were prospectively compared to simultaneous non-invasive cBP estimations using Antares, integrated into an oscillometric BP monitor. Antares analyses pulse waves during deflation of the cuff (patent of Redwave Medical GmbH). Generally speaking, pulse waves of a normal oscillometric BP measurement are taken for PWA with no need for altering standard BP pump operation.

Results: Mean difference between invasive and non-invasively estimated systolic cBP was 0.71 mmHg with standard deviation of 5.95 mmHg, fulfilling the highest validation criteria. Bland-Altman plot reveals good limits of agreement.

Conclusion: Antares is the first algorithm for estimation of cBP that entirely fulfills the 2017 ARTERY and AAMI/ESH/ISO validation protocols including criteria for high accuracy devices. The Antares algorithm turns the oscillometric upper arm blood pressure monitor into a type II-device for estimation of true cBP. Integration of Antares into BP monitors could enable the measurement of PWA parameters in virtually every practice in future.

Copyright
© 2019 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

Journal
Artery Research
Volume-Issue
25 - Supplement 1
Pages
S101 - S101
Publication Date
2020/02/17
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.2991/artres.k.191224.091How to use a DOI?
Copyright
© 2019 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - JOUR
AU  - Marcus Doerr
AU  - Stefan Richter
AU  - Siegfried Eckert
AU  - Marc-Alexander Ohlow
AU  - Fabian Hammer
AU  - Astrid Hummel
AU  - Vivien Dornberger
AU  - Elisabeth Genzel
AU  - Johannes Baulmann
PY  - 2020
DA  - 2020/02/17
TI  - P60 Invasive Validation of Antares, a New Algorithm to Calculate Central Blood Pressure from Oscillometric Upper Arm Pulse Waves
JO  - Artery Research
SP  - S101
EP  - S101
VL  - 25
IS  - Supplement 1
SN  - 1876-4401
UR  - https://doi.org/10.2991/artres.k.191224.091
DO  - 10.2991/artres.k.191224.091
ID  - Doerr2020
ER  -