Middle East respiratory syndrome coronavirus in Al-Madinah City, Saudi Arabia: Demographic, clinical and survival data
- 10.1016/j.jegh.2016.05.002How to use a DOI?
- Characteristics; Coronavirus; Epidemiology; MERS; Saudi Arabia; Survival
Background Middle East respiratory syndrome coronavirus (MERS-CoV), is an emerging virus respiratory infection. It has a high mortality rate and a wide spectrum of clinical features. This study describes the clinical characteristics and outcome of MERS infected patients.
Methods A retrospective study was conducted of all confirmed MERS-CoV infections from March 2014 to May 2014 at two tertiary care hospitals in Al-Madinah region (Saudi Arabia). We gathered data about demographic, clinical presentation, and factors associated with severity and mortality.
Results A total of 29 cases were identified; 20 males (69%) and nine females (31%), age 45 ± 12 years. The death rate was higher for men (52%) than for women (23%). Initial presentation was fever in 22 (75%) cases, cough in 20 (69%) cases, and shortness of breath in 20 (69%) cases. Associated comorbidities were diabetes mellitus in nine (31%) patients and chronic kidney disease (CKD) in eight (27%) patients. Duration of symptoms before hospitalization ranged from 2.9 days to 5 days. Elevated liver enzymes were present in 14 (50%) patients and impaired renal profile present in eight (27%) patients. We also describe in this study radiological patterns and factors associated with mortality.
Conclusion MERS-CoV infection transmission continues to occur as clusters in healthcare facilities. The frequency of cases and deaths is higher among men than women and among patients with comorbidities.
- © 2016 Ministry of Health, Saudi Arabia. Published by Elsevier Ltd.
- Open Access
- This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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TY - JOUR AU - Nahid Sherbini AU - Ayman Iskandrani AU - Ayman Kharaba AU - Ghalilah Khalid AU - Mohammed Abduljawad AU - Hamdan AL-Jahdali PY - 2016 DA - 2016/06/11 TI - Middle East respiratory syndrome coronavirus in Al-Madinah City, Saudi Arabia: Demographic, clinical and survival data JO - Journal of Epidemiology and Global Health SP - 29 EP - 36 VL - 7 IS - 1 SN - 2210-6014 UR - https://doi.org/10.1016/j.jegh.2016.05.002 DO - 10.1016/j.jegh.2016.05.002 ID - Sherbini2016 ER -