Journal of Epidemiology and Global Health

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Volume 6, Issue 3, September 2016, Pages 157 - 167

Evaluation of medication adherence in Lebanese hypertensive patients

Authors
Mohammad Yassine, Amal Al-Hajje, Sanaa Awada, Samar Rachidi, Salam Zein, Wafa Bawab, Mayssam Bou Zeid, Maya El Hajj, Pascale Salameh*, pascalesalameh1@hotmail.com
Clinical and Epidemiological Research Laboratory, Faculty of Pharmacy, Clinical Pharmacy Department, Doctoral School of Sciences & Technology, Lebanese University, Beirut, Lebanon
*Corresponding author at: Clinical Pharmacy Department, Lebanese University, Hadath, Beirut, Lebanon.
Corresponding Author
Received 6 April 2015, Revised 21 May 2015, Accepted 9 July 2015, Available Online 29 July 2015.
DOI
10.1016/j.jegh.2015.07.002How to use a DOI?
Keywords
Blood pressure; Hypertension; Lebanon; Medication adherence; Morisky scale
Abstract

Controlling hypertension is essential in cardiovascular diseases. Poor medication adherence is associated with poor disease outcomes, waste of healthcare resources, and contributes to reduced blood pressure control. This study evaluates treatment adherence to antihypertensive therapy in Lebanese hypertensive patients by estimating the proportion of adherent hypertensive patients using a validated tool and investigates what factors predict this behavior. A questionnaire-based cross-sectional study was conducted on a random sample of 210 hypertensive outpatients selected from clinics located in tertiary-care hospitals and from private cardiology clinics located in Beirut. Adherence level was measured using a validated 8-item Modified Morisky Medication Adherence Scale (MMMAS). Among 210 patients, 50.5% showed high adherence, 27.1% medium adherence, and 22.4% low adherence to medication. Mean MMMAS score was 6.59 ± 2.0. In bivariate analyses, having controlled blood pressure (p = 0.003) and taking a combination drug (p = 0.023) were predictors of high adherence. Forgetfulness (p < 0.01), complicated drug regimen (p = 0.001), and side effects (p = 0.006) were predictors of low adherence after multiple liner regression. Logistic regression results showed that calcium channel blockers (p = 0.030) were associated with increased adherence levels. In conclusion, developing multidisciplinary intervention programs to address the factors identified, in addition to educational strategies targeting healthcare providers, are necessary to enhance patient adherence.

Copyright
© 2015 Ministry of Health, Saudi Arabia. Published by Elsevier Ltd.
Open Access
This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)

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<Previous Article In Issue
Next Article In Issue>
Journal
Journal of Epidemiology and Global Health
Volume-Issue
6 - 3
Pages
157 - 167
Publication Date
2015/07/29
ISSN (Online)
2210-6014
ISSN (Print)
2210-6006
DOI
10.1016/j.jegh.2015.07.002How to use a DOI?
Copyright
© 2015 Ministry of Health, Saudi Arabia. Published by Elsevier Ltd.
Open Access
This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)

Cite this article

risenwbib
TY  - JOUR
AU  - Mohammad Yassine
AU  - Amal Al-Hajje
AU  - Sanaa Awada
AU  - Samar Rachidi
AU  - Salam Zein
AU  - Wafa Bawab
AU  - Mayssam Bou Zeid
AU  - Maya El Hajj
AU  - Pascale Salameh
PY  - 2015
DA  - 2015/07/29
TI  - Evaluation of medication adherence in Lebanese hypertensive patients
JO  - Journal of Epidemiology and Global Health
SP  - 157
EP  - 167
VL  - 6
IS  - 3
SN  - 2210-6014
UR  - https://doi.org/10.1016/j.jegh.2015.07.002
DO  - 10.1016/j.jegh.2015.07.002
ID  - Yassine2015
ER  -