Journal of Epidemiology and Global Health

<Previous Article In Issue
Next Article In Issue>
Volume 5, Issue Supplement 1, December 2015, Pages S67 - S71

Achieving high seroprevalence against polioviruses in Sri Lanka-Results from a serological survey, 2014

Authors
Deepa Gamagea, Paba Palihawadanaa, Ondrej Machb, *, macho@who.int, William C. Weldonc, Steven M. Oberstec, Roland W. Sutterb
aEpidemiology Unit, Ministry of Health, Sri Lanka
bPolio Eradication Department, World Health Organization, Geneva, Switzerland
cPolio and Picornavirus Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA
*Corresponding author at: Research and Product Development Team, Global Polio Eradication Initiative, World Health Organization, Avenue Appia 20, CH-1211 Genève 27, Switzerland.
Corresponding Author
Ondrej Machmacho@who.int
Received 28 January 2015, Revised 2 June 2015, Accepted 3 June 2015, Available Online 9 July 2015.
DOI
10.1016/j.jegh.2015.06.004How to use a DOI?
Keywords
Immunization; Poliomyelitis; Seroprevalence; Sri Lanka
Abstract

The immunization program in Sri Lanka consistently reaches >90% coverage with oral poliovirus vaccines (OPV), and no polio supplementary vaccination campaigns have been conducted since 2003. We evaluated serological protection against polioviruses in children. A cross-sectional community-based survey was performed in three districts of Sri Lanka (Colombo, Badulla, and Killinochi). Randomly selected children in four age groups (9–11 months, 3–4 years, 7–9 years, and 15 years) were tested for poliovirus neutralizing antibodies. All 400 enrolled children completed the study. The proportion of seropositive children for poliovirus Type 1 and Type 2 was >95% for all age groups; for poliovirus Type 3 it was 95%, 90%, 77%, and 75% in the respective age groups. The vaccination coverage in our sample based on vaccination cards or parental recall was >90% in all age groups. Most Sri Lankan children are serologically protected against polioviruses through routine immunization only. This seroprevalence survey provided baseline data prior to the anticipated addition of inactivated poliovirus vaccine (IPV) into the Sri Lankan immunization program and the switch from trivalent OPV (tOPV) to bivalent OPV (bOPV).

Copyright
© 2015 Ministry of Health, Saudi Arabia. Published by Elsevier Ltd.
Open Access
This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

Download article (PDF)
View full text (HTML)

<Previous Article In Issue
Next Article In Issue>
Journal
Journal of Epidemiology and Global Health
Volume-Issue
5 - Supplement 1
Pages
S67 - S71
Publication Date
2015/07/09
ISSN (Online)
2210-6014
ISSN (Print)
2210-6006
DOI
10.1016/j.jegh.2015.06.004How to use a DOI?
Copyright
© 2015 Ministry of Health, Saudi Arabia. Published by Elsevier Ltd.
Open Access
This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

Cite this article

risenwbib
TY  - JOUR
AU  - Deepa Gamage
AU  - Paba Palihawadana
AU  - Ondrej Mach
AU  - William C. Weldon
AU  - Steven M. Oberste
AU  - Roland W. Sutter
PY  - 2015
DA  - 2015/07/09
TI  - Achieving high seroprevalence against polioviruses in Sri Lanka-Results from a serological survey, 2014
JO  - Journal of Epidemiology and Global Health
SP  - S67
EP  - S71
VL  - 5
IS  - Supplement 1
SN  - 2210-6014
UR  - https://doi.org/10.1016/j.jegh.2015.06.004
DO  - 10.1016/j.jegh.2015.06.004
ID  - Gamage2015
ER  -