Research on Concanavalin A Crystallization in a Flow-Free Droplet-Based Device
Guan-ru DU, Wen-jun ZHANG, Ding-kun JI, Feng-juan CHEN, Di YIN, Hong-bo ZHANG, Rui-xue YIN, Xiao-peng HE, Shih-Mo YANG
Available Online May 2017.
- 10.2991/bbe-17.2017.70How to use a DOI?
- Protein, Crystallization, Droplet-based.
Protein crystallography is a very critical process that limits the development of pharmaceutical engineering. Microfluidic technology has provided an opportunity for protein crystallization. In this paper, a flow-free droplet-based device is presented for producing highly controlled crystals and fabrication of this device with polydimethylsiloxane (PDMS) is presented. The experiment was performed on the device and shows that the crystals of Con A and protein ligand (DK3) have a spherical structure.
- © 2017, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Guan-ru DU AU - Wen-jun ZHANG AU - Ding-kun JI AU - Feng-juan CHEN AU - Di YIN AU - Hong-bo ZHANG AU - Rui-xue YIN AU - Xiao-peng HE AU - Shih-Mo YANG PY - 2017/05 DA - 2017/05 TI - Research on Concanavalin A Crystallization in a Flow-Free Droplet-Based Device BT - Proceedings of the 2nd International Conference on Biomedical and Biological Engineering 2017 (BBE 2017) PB - Atlantis Press SP - 435 EP - 439 SN - 2468-5747 UR - https://doi.org/10.2991/bbe-17.2017.70 DO - 10.2991/bbe-17.2017.70 ID - DU2017/05 ER -