Use Text Mining and Complex Networks to Analyze TCM Syndromes

DOI

10.2991/bbe-17.2017.78How to use a DOI?

Keywords

Text mining, Complex network, Traditional Chinese medicine.

Abstract

Objective: To make intrinsic biological distinctions between qi deficiency pattern and qi stagnation pattern with genes related to NEI. Methods: Establish a data dictionary of NEI-related genes and a keyword lexicon of qi deficiency pattern and qi stagnation pattern. Then retrieve relevant literature on Pubmed database. Obtain compositions of characteristic NEI-related genes of qi deficiency pattern and qi stagnation pattern by using text-mining methodto explore different bioactive materials between the two syndromes. Results: Two kinds of syndromes and their biological networks were constructed. The "qi deficiency" and "qi stagnation" genes based on NEI network were excavated. Conclusion: The genes of qi stagnation pattern relate closely with nerve and endocrine, while those of qi deficiency pattern have a close relationship with the immune system. The intrinsic biological characterizations of TCM patterns can be effectively identified at the level of NEI.

Copyright

© 2017, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Xing ZHAI
AU  - Ping WANG
AU  - You-liang HUANG
PY  - 2017/05
DA  - 2017/05
TI  - Use Text Mining and Complex Networks to Analyze TCM Syndromes
BT  - Proceedings of the 2nd International Conference on Biomedical and Biological Engineering 2017 (BBE 2017)
PB  - Atlantis Press
SP  - 486
EP  - 491
SN  - 2468-5747
UR  - https://doi.org/10.2991/bbe-17.2017.78
DO  - 10.2991/bbe-17.2017.78
ID  - ZHAI2017/05
ER  -