Proceedings of the conference BioSangam 2022: Emerging trends in Biotechnology (BIOSANGAM 2022)

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Genome Scale Pathway-Pathway Co-functional Synergistic Network (PcFSN) in Oryza Sativa

Authors
Chittabrata Mal1, *, Ayushman Kumar Banerjee1, Joyabrata Mal2
1Department of Bioinformatics, Maulana Abul Kalam Azad University of Technology, West Bengal, Nadia, India
2Department of Biotechnoloygy, MNNIT Allahabad, Prayagraj, India
*Corresponding author. Email: chittabrata@gmail.com Email: chittabrata.mal@makautwb.ac.in
Corresponding Author
Chittabrata Mal
Available Online 14 December 2022.
DOI
10.2991/978-94-6463-020-6_6How to use a DOI?
Keywords
miRNA; synergistic network; modules; genome scale
Abstract

Cohesive network modelling and systems biology have emerged as extremely potent tools which helps understanding the combinatorial effects of biomolecules. Synergistic modulation among biomolecules (e.g., enzymes, transcription factors, microRNAs, drugs, etc.) are significant in finding out complex regulatory mechanisms in biological networks and pathways. In some cases, although combinatorial interactions among some biomolecules in specific biological networks is available, our knowledge in that particular domain is very limited with context to a genomic scale. Here we explore the pathway-pathway network to identify and understand the network architecture of metabolic pathway mediated regulations at genomic and co-functional levels, in rice. Using network transformation methods, a genome scale pathway-pathway co-functional synergistic network (PcFSN) was constructed. Finally, the PcFSN modules are extracted. This in turn helps to identify the miRNAs and genes associated with the pathways, especially linked to the central metabolic network in rice.

Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the conference BioSangam 2022: Emerging trends in Biotechnology (BIOSANGAM 2022)
Series
Advances in Biological Sciences Research
Publication Date
14 December 2022
ISBN
10.2991/978-94-6463-020-6_6
ISSN
2468-5747
DOI
10.2991/978-94-6463-020-6_6How to use a DOI?
Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

risenwbib
TY  - CONF
AU  - Chittabrata Mal
AU  - Ayushman Kumar Banerjee
AU  - Joyabrata Mal
PY  - 2022
DA  - 2022/12/14
TI  - Genome Scale Pathway-Pathway Co-functional Synergistic Network (PcFSN) in Oryza Sativa
BT  - Proceedings of the conference BioSangam 2022: Emerging trends in Biotechnology (BIOSANGAM 2022)
PB  - Atlantis Press
SP  - 47
EP  - 57
SN  - 2468-5747
UR  - https://doi.org/10.2991/978-94-6463-020-6_6
DO  - 10.2991/978-94-6463-020-6_6
ID  - Mal2022
ER  -