Proceedings of the conference BioSangam 2022: Emerging trends in Biotechnology (BIOSANGAM 2022)

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27 articles
Proceedings Article

Peer-Review Statements

Vishnu Agarwal, Rupika Sinha, Joyabrata Mal
All of the articles in this proceedings volume have been presented at the Biosangam 2022 during March 10–12, 2022 in Prayagraj. These articles have been peer reviewed by the members of the Review Committee and approved by the Editor-in-Chief, who affirms that this document is a truthful description of...
Proceedings Article

Biofilm Detachment and Its Implication in Spreading Biofilm-Related Infections

Akshat Gupta, Anmol Srivastava, Vishnu Agarwal
Biofilms are a community of microorganisms formed on both abiotic and biotic surfaces. These colonies play a vital role in the virulent life cycle of bacteria. Bacteria communicate intrinsically and extrinsically to grow and eventually disperse their virulent factors, ultimately leading to diseases....
Proceedings Article

Nanotechnology in COVID-19 Vaccines

Ananya Jain, Shilpa Sharma
Nanotechnology has been proposed in vaccine development as carriers and adjuvants time and again but received limited recognition before the development of vaccines for the COVID-19 pandemic. Nanotechnology has played a pivotal role in the triumph of the vaccines for the current pandemic caused by the...
Proceedings Article

Antimicrobial Activity of Some Essential Oils Against Pseudomonas aeruginosa

Anmol Srivastava, Vivek Kumar, Vishnu Agarwal
The emergence of multidrug resistance in bacteria due to overuse of antibiotics is becoming an important health concern in recent years, which requires development of novel alternatives to fight against these bacteria. Essential oils (EOs) are secondary metabolites that have different components and...
Proceedings Article

Challenges in Drug Delivery Through Intranasal Route: A CFD Perspective

Anurag Tiwari, Akshoy Ranjan Paul, Anuj Jain
The paper discusses the various challenges encountered during drug delivery through intranasal routes. It also investigates how the computational fluid dynamics (CFD) is effectively utilized by the researchers in mitigating these challenges and to develop a efficient intranasal drug delivery device.
Proceedings Article

Genome Scale Pathway-Pathway Co-functional Synergistic Network (PcFSN) in Oryza Sativa

Chittabrata Mal, Ayushman Kumar Banerjee, Joyabrata Mal
Cohesive network modelling and systems biology have emerged as extremely potent tools which helps understanding the combinatorial effects of biomolecules. Synergistic modulation among biomolecules (e.g., enzymes, transcription factors, microRNAs, drugs, etc.) are significant in finding out complex regulatory...
Proceedings Article

Phytochemicals as Potential Drug Candidates for SARS Cov-2: An RDRp Based In-Silico Drug Designing

Christy Joy, Marria C. Cyriac
The global pandemic that the world is currently witnessing, COVID-19, even with vaccines available, the test positivity rate (TPR) tends to remain highly threatening. This research focuses on identifying phytochemicals, previously known for their broad-spectrum antiviral properties which can be potential...
Proceedings Article

Microbial Enzymes: A Summary Focusing on Biotechnology Prospective for Combating Industrial Pollutants

Debosmita Sikdar, Ivy Kanungo, Dipanwita Das
Environmental issues are growing at an alarming rate and addressing the same is the need of the hour. Hazardous industrial pollutants and discharges are adding to the misery. Therefore, new ideas and technologies are being created and adopted to deal with ever increasing conservational troubles. Due...
Proceedings Article

Nanozymes for Neurodegenerative Diseases

Divyansh Yadav, Seema Nara
Neurodegenerative diseases are incurable diseases that get worse as time passes. These diseases are very heterogeneous in nature but have common characteristics like abnormal deposition of protein, glycation, inflammation in particular areas of the brain, and progressive neuronal loss due to oxidative...
Proceedings Article

Mini-review on Inhibitors of Human Tyrosinase

Jyoti Srivastava, Joyabrata Mal, Manju Verma, Rupika Sinha
Melanin is a major pigment of human skin that protects the skin from harmful ultraviolet radiation, DNA damage and oxidative stress. However, the excess accumulation of melanin may lead to various hyperpigmentation-related diseases. Tyrosinase is a copper containing enzyme that regulates the rate-limiting...
Proceedings Article

Revisiting the Genomics and Genetic Codes Using Walsh-Hadamard Spectrum Analysis

Mayasar Ahmad Dar, Deepmala Sharma
Walsh-Hadamard spectrum is widely used in the field of science and technology like classification of cancer cells, image processing, speech processing, signal and image compression etc. In this paper, a genomic analysis using Walsh-Hadamard spectrum and cross-correlation has been done. Transformation...
Proceedings Article

Phylogenetic Characterization of Nitrifying Bacteria Isolated from East Kolkata Wetland

Mousumi Saha, Agniswar Sarkar, Bidyut Bandyopadhyay
East Kolkata Wetland (EKW) is an “International Ramsar Site”, famous for broad biodiversity and insightful use of sewage for aquaculture. Native nitrifying bacteria of EKW play a significant role in maintaining water quality and controlling environmental pollution by converting ammonia into nitrate in...
Proceedings Article

A Review on Current Strategies for Biofilm Control in Food Industry

Nidhi Verma, Vishnu Agarwal
Biofilms are still a serious threat to the world. Biofilms are formed due to the natural tendency of microorganisms according to environmental factors. And they are solicitude in many fields counting food, medical and environmental. Biofilms are hard to exterminate due to their resistant phenotype. Since...
Proceedings Article

CoSSDb: A Database of Co-crystallized Ligand Sub-structures for Anticancer Lead Designing & Optimization

Om Prakash, Feroz Khan
The Discovery of the novel optimized structures of small molecules for selective targeting is one of the challenging tasks in drug designing. Bioisosteres are the key components of the lead compound, which provide hidden power to the compound scaffold for selective targeting. We are presenting a database,...
Proceedings Article

Exploring Molecular Signatures in Spondyloarthritis: A Step Towards Early Diagnosis

Parinishtha Bhalla, Anukriti Verma, Bhawna Rathi, Shivani Sharda, Pallavi Somvanshi
Spondyloarthritis is an acute inflammatory disorder of the musculoskeletal system often accompanied by pain, stiffness, bone and tissue damage. It majorly consists of ankylosing spondylitis, psoriatic arthritis and reactive arthritis. It follows a differential diagnosis pattern for demarcation between...
Proceedings Article

Green Synthesis of Silver Nanoparticles from Madhuca longifolia and Its Antibiofilm Potential

Poonam Kaithal, Rajiv Kant, Rohit Lall, Archana Verma, Preetam Verma
The synthesis of silver nanoparticles using plant extract as a capping agent has been very easy, economical and environment friendly method. The Madhuca longifolia is one of the well-known trees for its various benefits from food industry to its medicinal applications. It is indigenous to India, Nepal,...
Proceedings Article

Loss of Function of Sth1, The Catalytic Component of RSC (Remodel the Structure of Chromatin) Complex Grossly Alter the Chromatin Architecture

Priya Prasad
Chromatin architecture has a profound effect on the gene expression in eukaryotes. It is constantly modulated in the cells in response to different stress condition and during the normal physiological process in the cell. The chromatin is also modulated during the cell growth and division, where several...
Proceedings Article

Prognostic Importance of Th1:Th2 (IL-1β/IL-10) Cytokine Ratio in Adult Onset-Bronchial Asthma

Rabia Tahseen, Mohammad Parvez, G. Sravan Kumar, Parveen Jahan
Bronchial asthma is a complex respiratory disorder, exhibits several endotypes and phenotypes due to different underlying cellular and molecular mechanisms. Globally it affects 300 million individuals, with the prevalence of 2–3% in India, contributing to morbidity and mortality. Over 50 cytokines have...
Proceedings Article

In Vitro Anticancer Screening of Methanolic Extract of Stachytarpheta Mutabilis

Ramesh Londonkar, Maithilee Kesralikar
In therapeutic plants, phytochemicals are found in abundance. A family of verbena known as vervain (verbenaceae) consists of over 100 genera and nearly 2600 species. Among the Verbenaceae family is Stachytarpheta, a green perennial herb. The species is being examined in this study for its phytochemical,...
Proceedings Article

Docking and Molecular Dynamics Simulation Studies for the Evaluation of Laccase Mediated Biodegradation of Triclosan

G. Ranimol, C. B. Devipriya, Swetha Sunkar
Triclosan (TCA) is an antibacterial and antimicrobial compound that is incorporated into toothpaste, soap, and liquid dishwasher. Continuous TCA exposure may contribute to the emergence of antibiotic-resistant bacteria in the microbiome. Triclosan also reacts to form dioxins, which bioaccumulate and...
Proceedings Article

Effect of Calcium Silicate Supplementation on the Growth of Trigonella Foenum-Graecum L. Variety Hisar Sonali Under Saline Conditions

Riti Thapar Kapoor
Salinity is a major abiotic stress which decreases crop productivity. Salt stress also causes osmotic, water, ionic and oxidative stresses. Plants exposure to salt can check their growth by reduction in water and nutrient uptake, osmotic imbalance and cytotoxicity incited by sodium and chloride ions....
Proceedings Article

Allozyme Diversity Inforensically Important Indian Species Chrysomya Megacephala (Fabricius) (Diptera: Calliphoridae)

Sarita Agrawal, Shubhra Malviya
The application of electrophoretic technique to study allozyme enzymatic variation has been extensively used to explore hidden genetic variability in natural population and laboratory colonies of many calliphorid flies. Genetic variation at three enzyme loci viz., Alkaline phosphatase (APH), Xanthin...
Proceedings Article

A Review on Some Gymnospermous Fructifications from the Triassic of Nidpur, Madhya Pradesh, India

Shabnam Parveen
The Nidpur bed was discovered near Nidpur village, Sidhi District, Madhya Pradesh, India. The carbonized fossils of Nidpur beds comprise plant remains assignable to different groups of the plant kingdom like algae, bryophytes, pteridophytes and gymnosperms. The gymnospermous remains often occur as detached...
Proceedings Article

RAPD-PCR-Based Genetic Relationships Among Three Forensically Important Calliphorid Species (Diptera: Calliphoridae)

Shubhra Malviya, Sarita Agrawal
Molecular genetic markers have been effectively used to analyze genetic relationships and diversity among different groups of dipterans. The emergence of Polymerase Chain Reaction (PCR) facilitated analysis of molecular markers e.g., Random Amplified Polymorphic DNA-Polymerase Chain Reaction (RAPD-PCR),...
Proceedings Article

The Feasibility Study of Green Microalgae Assisted Coal Mine Effluent Desalination

Shweta Rawat, Sanjay Kumar
Carbon-neutral sustainable approaches are highly demanding in the coal energy sector. Coal mine effluent disposal is a severe challenge with crucial concern issues of salinity hazard and heavy metal contamination due to long-duration water and coal interaction. The medium to the high salinity of coal...
Proceedings Article

Analysis of Pectin in Different Citrus Fruits and Evolutionary Relationship

Upashna Upadhyay, Poonam Kaithal, Preetam Verma, Rohit Lall, Poonam Singh
Pectin is a polysaccharide present in fruit cell walls can be extracted from fruit wastes obtained after processing. The objective of the present investigation was to study the potential of citrus fruit peels to be a source of pectin as it is of great importance in food and medical industry. This study...
Proceedings Article

Pomegranate Extract Protects Endothelial Cells from TNF-α Associated Damage

Ravindran Vini, Sreeja Sreekumar, Juberiya M. Azeez, Sreeja Sreeharshan
Pomegranates are known for being rich in polyphenols and are considered to have immense therapeutic potential. The present study investigates the hypothesis that the Methanolic Extract of Pomegranate (PME), a rich source of antioxidants, may reverse the adverse effects of TNF-α in endothelial cells....