Proceedings of the 2017 2nd International Conference on Biological Sciences and Technology (BST 2017)

Degradation, Characterization, Ferrous Ion Chelating Ability and Repair Effect of Sulfated Polysaccharides of Six Kinds of Seaweed Polysaccharides

Authors
Xin-Yuan Sun, Da Guo, Jian-Min Wang, Jian-Ming Ouyang
Corresponding Author
Xin-Yuan Sun
Available Online February 2018.
DOI
https://doi.org/10.2991/bst-17.2018.32How to use a DOI?
Keywords
Antioxidant, Cell repair, Sulfated polysaccharides
Abstract

Six kinds of seaweed polysaccharides (SPSs) extracted from Laminaria japonica, Porphyra yezoensis, Gracilaria lemaneiformis, Sargassum fusiforme, Eucheuma gelatinae and Undaria pinnatifida were degraded and characterized. The sulfate group (-OSO3H) content of these polysaccharides were 21.7, 17.9, 13.3, 8.2, 7.0, and 5.5%, respectively. The ferrous ion chelating ability and repair effect on injured human kidney proximal tubular epithelial cells (HK-2) of these polysaccharides were studied. These polysaccharides had stronger ferrous ion chelating ability, suggesting that it possessed high antioxidant activity. Each polysaccharide had a repair effect on oxalate-induced damaged HK-2 cells. The antioxidant activity and repair ability of polysaccharide was positively correlated with its -OSO3H content. These results indicated that these polysaccharides, especially those with high -OSO3H content, may be potential drugs for the prevention and treatment of calcium oxalate stones.

Copyright
© 2018, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the 2017 2nd International Conference on Biological Sciences and Technology (BST 2017)
Series
Advances in Biological Sciences Research
Publication Date
February 2018
ISBN
978-94-6252-472-9
ISSN
2468-5747
DOI
https://doi.org/10.2991/bst-17.2018.32How to use a DOI?
Copyright
© 2018, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - CONF
AU  - Xin-Yuan Sun
AU  - Da Guo
AU  - Jian-Min Wang
AU  - Jian-Ming Ouyang
PY  - 2018/02
DA  - 2018/02
TI  - Degradation, Characterization, Ferrous Ion Chelating Ability and Repair Effect of Sulfated Polysaccharides of Six Kinds of Seaweed Polysaccharides
BT  - Proceedings of the 2017 2nd International Conference on Biological Sciences and Technology (BST 2017)
PB  - Atlantis Press
SP  - 220
EP  - 226
SN  - 2468-5747
UR  - https://doi.org/10.2991/bst-17.2018.32
DO  - https://doi.org/10.2991/bst-17.2018.32
ID  - Sun2018/02
ER  -