Allopurinol Administration: When is More Effective?
Yedy Purwandi Sukmawan, Keni Idacahyati, Wina Widiyanti
Yedy Purwandi Sukmawan
Available Online 8 June 2020.
- 10.2991/ahsr.k.200523.077How to use a DOI?
- allopurinol, uric acid, hyperuricemia
Objectives: The objective of the study was to determine the appropriate administration time of allopurinol between morning and night administration. Method: This research was conducted in a controlled and open label. Eleven patients (six in night and five in morning) were fulfilled the criteria. Results and Discussion: no significant difference in the uric acid reduction between night and morning administration (p 0.435). However, night administration of allopurinol showed lower uric acid level reduction (-2.45 vs -0.98). In adverse reactions events, the night administration of allopurinol contributed to nausea and flatulence. Conclusion: Allopurinol provides better uric acid reduction at night but should be caution of the side effects.
- © 2020, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Yedy Purwandi Sukmawan AU - Keni Idacahyati AU - Wina Widiyanti PY - 2020 DA - 2020/06/08 TI - Allopurinol Administration: When is More Effective? BT - The proceedings of the 2nd Bakti Tunas Husada-Health Science International Conference (BTH-HSIC 2019) PB - Atlantis Press SP - 324 EP - 325 SN - 2468-5739 UR - https://doi.org/10.2991/ahsr.k.200523.077 DO - 10.2991/ahsr.k.200523.077 ID - Sukmawan2020 ER -