Inhibitory Activity of Tyrosinase Enzyme on Lotion Contains Pear (Pyrus pyrifolia (Burm.F) Nakai) Rind Extract
Deby Tristiyanti, Ledianasari, Silva Oktaviani
Available Online 8 June 2020.
- https://doi.org/10.2991/ahsr.k.200523.022How to use a DOI?
- pears (Pyrus pyrifolia (Burm.f.) Nakai), skin lightening, lotion, tyrosinase enzyme
- Objectives: The purpose of this study was to make lotion preparations containing ethanol extract of pear rind and to test the inhibitory activity of the tyrosinase enzyme from pear rind ethanol extract lotion preparations. Method: Determination of tyrosinase enzyme inhibitory activity was carried out using a microplate reader instrument. The formula used is ethanol extract of pear rind, stearic acid, cetyl alcohol, triethanolamine, liquid paraffin, glycerin, sodium benzoate, essense pear and distilled water. Results and Discussion: Ethanol extract of pear rind has tyrosinase enzyme inhibiting activity which is indicated by IC50 values of 520.45 μg/mL, and in lotion preparations it has tyrosinase enzyme inhibitory activity which is indicated by IC50 values of 599.96 μg/mL. Conclusion: From the results of tyrosinase inhibitory activity test, lotion containing ethanol extract of pear rind has the potential to be a skin lightening.
- Open Access
- This is an open access article distributed under the CC BY-NC license.
Cite this article
TY - CONF AU - Deby Tristiyanti AU - Ledianasari AU - Silva Oktaviani PY - 2020 DA - 2020/06/08 TI - Inhibitory Activity of Tyrosinase Enzyme on Lotion Contains Pear (Pyrus pyrifolia (Burm.F) Nakai) Rind Extract BT - 2nd Bakti Tunas Husada-Health Science International Conference (BTH-HSIC 2019) PB - Atlantis Press SP - 88 EP - 91 SN - 2468-5739 UR - https://doi.org/10.2991/ahsr.k.200523.022 DO - https://doi.org/10.2991/ahsr.k.200523.022 ID - Tristiyanti2020 ER -