The Research Progress of Transforming Growth Factor (TGF - Beta) Gene Regulation and Invasion and Metastasis of Pancreatic Cancer

DOI

10.2991/cmes-15.2015.150How to use a DOI?

Keywords

transforming growth factors-; gene expression; pancreatic cancer; invasion and metastasis

Abstract

Transforming growth factors TGF is a kind of a superfamily of peptides, which have strong sensitivity to cell proliferation differention and transfer, its function and its structure are very complicated, and it is a cell factor which widely exist in multiple cells. There are more and more attention on it in the recent years, especially the relation with the tumor is become a key point. TGF- can inhibit related proteins and gene regulation at the early stages of the tumor ,,so can effect the cell proliferation, but at the late stages the tumor, TGF- can also promote the invasion and matastasis of tumor cells. The important feature of pancreatic cancer is a highly mortality rate. But TGF- have two-direction adjust effect to tumor. This article is mainly to the TGF - beta gene expression and the mechanisms and the invasion and metastasis of pancreatic cancer are reviewed in this paper.

Copyright

© 2015, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Xiao-jing Gong
AU  - Guiqing Yang
AU  - Dongning Sun
AU  - Lingqin Wan
AU  - Yi-shan Wang
PY  - 2015/04
DA  - 2015/04
TI  - The Research Progress of Transforming Growth Factor (TGF - Beta) Gene Regulation and Invasion and Metastasis of Pancreatic Cancer
BT  - Proceedings of the 2nd International Conference on Civil, Materials and Environmental Sciences
PB  - Atlantis Press
SP  - 537
EP  - 541
SN  - 2352-5401
UR  - https://doi.org/10.2991/cmes-15.2015.150
DO  - 10.2991/cmes-15.2015.150
ID  - Gong2015/04
ER  -