Proceedings of the 2016 6th International Conference on Applied Science, Engineering and Technology

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Effect of Cortex Lycii Radicis Ethanol-Extract on the Hypoglycemic and Hypolipidemic In Type 2 Diabetic Rats

Authors
Changlei Li, Xiji Shu, Xiaoqing Chen, Yuwei Liu, Huiling Yi, Wei Liu, Baomiao Ma
Corresponding Author
Changlei Li
Available Online May 2016.
DOI
10.2991/icaset-16.2016.60How to use a DOI?
Keywords
Cortex lycii radicis ethanol-extract, Type 2 diabetic mellitus(T2DM), Hypoglycemic, Hypolipidemic
Abstract

To observe effect of cortex lycii radicis ethanol-extract on the hypoglycemic and hypolipidemic in T2DM rats. T2DM rat modelinduced by intravenous injection small dose of streptozotocin (STZ) and feeding high fat-high glucose diet .The rats were randomly divided into blank control group, model control group, cortex lycii radicis ethanol-extract groups of high dose, medium dose and low dose, positive drug rosiglitazone group. Seven weeks after medication, to observe influence of cortex lycii radicis ethanol-extract on rat weight and the content in fasting blood glucose (FBG), serum insulin(INS), total cholesterol(TC), triglycerides(TG) and low density lipoprotein cholesterol (LDL-C). Compared blank control group with the other groups, there were no significant differences in various indicators of be detected(P>0.05). Compared with the model group, cortex lycii radicis ethanol-extract can reduced body weight, FBG, INS, TC, TG and LDL-C, increased INS of T2DM rats, the differences were significant (P<0.01or 0.05).Cortex lycii radicis ethanol-extract can lowers blood glucose and regulate blood lipid metabolism to some extent.

Copyright
© 2016, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the 2016 6th International Conference on Applied Science, Engineering and Technology
Series
Advances in Engineering Research
Publication Date
May 2016
ISBN
10.2991/icaset-16.2016.60
ISSN
2352-5401
DOI
10.2991/icaset-16.2016.60How to use a DOI?
Copyright
© 2016, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

risenwbib
TY  - CONF
AU  - Changlei Li
AU  - Xiji Shu
AU  - Xiaoqing Chen
AU  - Yuwei Liu
AU  - Huiling Yi
AU  - Wei Liu
AU  - Baomiao Ma
PY  - 2016/05
DA  - 2016/05
TI  - Effect of Cortex Lycii Radicis Ethanol-Extract on the Hypoglycemic and Hypolipidemic In Type 2 Diabetic Rats
BT  - Proceedings of the 2016 6th International Conference on Applied Science, Engineering and Technology
PB  - Atlantis Press
SP  - 303
EP  - 307
SN  - 2352-5401
UR  - https://doi.org/10.2991/icaset-16.2016.60
DO  - 10.2991/icaset-16.2016.60
ID  - Li2016/05
ER  -