Proceedings of the 12th International Conference on Green Technology (ICGT 2022)

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Synthesis of Schiff Base Compounds from 4-Formilpyridine and P-Anisidina Using Sonication Method as Antibacterial

Authors
Ahmad Hanapi1, *, Lutfiyatul Hasanah1, Rachmawati Ningsih1, Himmatul Barroroh1
1Department of Chemistry, Universitas Islam Negeri Maulana Malik Ibrahim, Malang, Indonesia
*Corresponding author. Email: hanapi_ahmad@kim.uin-malang.ac.id
Corresponding Author
Ahmad Hanapi
Available Online 29 May 2023.
DOI
10.2991/978-94-6463-148-7_38How to use a DOI?
Keywords
Schiff base; 4-Formylpyridine; p-Anisidine; Sonication Method; Antibacterial
Abstract

Schiff base compounds are reported to have various biological activities, one of which is antibacterial. This study aims to determine the characterization of the Schiff base product with the sonication method and to determine its antibacterial activity. Schiff base products from 4formylpyridine and panisidine were characterized using FTIR, KG-SM, and 1H-NMR as well as antibacterial activity tests. The results of the characterization using FTIR produced a wave number of 1621 cm−1 which was thought to be the absorption of the C = N group which was the target compound, and the KG-SM characterization showed the presence of the target compound for the synthesis of 4-methoxy-N(pyridine-4-ylmethylene)aniline at m/ z 212. Meanwhile, the 1H-NMR characterization of the product showed the presence of a singlet proton imine signal at a chemical shift of 8.46 ppm (1H, s), as well as the presence of antibacterial activity that was effective in inhibiting bacterial growth at a concentration of 10,000 μg/mL.

Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the 12th International Conference on Green Technology (ICGT 2022)
Series
Advances in Engineering Research
Publication Date
29 May 2023
ISBN
10.2991/978-94-6463-148-7_38
ISSN
2352-5401
DOI
10.2991/978-94-6463-148-7_38How to use a DOI?
Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

risenwbib
TY  - CONF
AU  - Ahmad Hanapi
AU  - Lutfiyatul Hasanah
AU  - Rachmawati Ningsih
AU  - Himmatul Barroroh
PY  - 2023
DA  - 2023/05/29
TI  - Synthesis of Schiff Base Compounds from 4-Formilpyridine and P-Anisidina Using Sonication Method as Antibacterial
BT  - Proceedings of the 12th International Conference on Green Technology (ICGT 2022)
PB  - Atlantis Press
SP  - 386
EP  - 393
SN  - 2352-5401
UR  - https://doi.org/10.2991/978-94-6463-148-7_38
DO  - 10.2991/978-94-6463-148-7_38
ID  - Hanapi2023
ER  -